Yao Y - Search Results

1

Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.

Liu Z, Yao Y, Kogiso M, Zheng B, Deng L, Qiu JJ, Dong S, Lv H, Gallo JM, Li XN, Song Y. Liu Z, et al. Among authors: yao y. J Med Chem. 2014 Oct 23;57(20):8307-18. doi: 10.1021/jm500660f. Epub 2014 Oct 1. J Med Chem. 2014. PMID: 25271760 Free PMC article.

2

Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies.

Deng L, Diao J, Chen P, Pujari V, Yao Y, Cheng G, Crick DC, Prasad BV, Song Y. Deng L, et al. Among authors: yao y. J Med Chem. 2011 Jul 14;54(13):4721-34. doi: 10.1021/jm200363d. Epub 2011 Jun 2. J Med Chem. 2011. PMID: 21561155 Free PMC article.

3

Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies.

Yao Y, Chen P, Diao J, Cheng G, Deng L, Anglin JL, Prasad BV, Song Y. Yao Y, et al. J Am Chem Soc. 2011 Oct 26;133(42):16746-9. doi: 10.1021/ja206312b. Epub 2011 Oct 4. J Am Chem Soc. 2011. PMID: 21936531 Free PMC article.

4

Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L.

Anglin JL, Deng L, Yao Y, Cai G, Liu Z, Jiang H, Cheng G, Chen P, Dong S, Song Y. Anglin JL, et al. Among authors: yao y. J Med Chem. 2012 Sep 27;55(18):8066-74. doi: 10.1021/jm300917h. Epub 2012 Sep 6. J Med Chem. 2012. PMID: 22924785 Free PMC article.

5

Antimalarial and Structural Studies of Pyridine-containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase.

Xue J, Diao J, Cai G, Deng L, Zheng B, Yao Y, Song Y. Xue J, et al. Among authors: yao y. ACS Med Chem Lett. 2013 Feb 14;4(2):278-282. doi: 10.1021/ml300419r. ACS Med Chem Lett. 2013. PMID: 23795240 Free PMC article.

6

Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase.

Zheng B, Yao Y, Liu Z, Deng L, Anglin JL, Jiang H, Prasad BV, Song Y. Zheng B, et al. Among authors: yao y. ACS Med Chem Lett. 2013 Jun 13;4(6):542-546. doi: 10.1021/ml400036z. ACS Med Chem Lett. 2013. PMID: 23795241 Free PMC article.

7

Synthesis, Activity and Metabolic Stability of Non-Ribose Containing Inhibitors of Histone Methyltransferase DOT1L.

Deng L, Zhang L, Yao Y, Wang C, Redell MS, Dong S, Song Y. Deng L, et al. Among authors: yao y. Medchemcomm. 2013 May 1;4(5):822-826. doi: 10.1039/C3MD00021D. Medchemcomm. 2013. PMID: 23795283 Free PMC article.

8

Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer.

Zhang L, Deng L, Chen F, Yao Y, Wu B, Wei L, Mo Q, Song Y. Zhang L, et al. Among authors: yao y. Oncotarget. 2014 Nov 15;5(21):10665-77. doi: 10.18632/oncotarget.2496. Oncotarget. 2014. PMID: 25359765 Free PMC article.

9

Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.

Wu F, Jiang H, Zheng B, Kogiso M, Yao Y, Zhou C, Li XN, Song Y. Wu F, et al. Among authors: yao y. J Med Chem. 2015 Sep 10;58(17):6899-6908. doi: 10.1021/acs.jmedchem.5b00684. Epub 2015 Aug 26. J Med Chem. 2015. PMID: 26280302 Free PMC article.

10

3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1.

Wu F, Zhou C, Yao Y, Wei L, Feng Z, Deng L, Song Y. Wu F, et al. Among authors: yao y. J Med Chem. 2016 Jan 14;59(1):253-263. doi: 10.1021/acs.jmedchem.5b01361. Epub 2015 Dec 24. J Med Chem. 2016. PMID: 26652247 Free PMC article.

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