Qiu JJ - Search Results

1

Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.

Liu Z, Yao Y, Kogiso M, Zheng B, Deng L, Qiu JJ, Dong S, Lv H, Gallo JM, Li XN, Song Y. Liu Z, et al. Among authors: qiu jj. J Med Chem. 2014 Oct 23;57(20):8307-18. doi: 10.1021/jm500660f. Epub 2014 Oct 1. J Med Chem. 2014. PMID: 25271760 Free PMC article.

2

Oncogenic features of PHF8 histone demethylase in esophageal squamous cell carcinoma.

Sun X, Qiu JJ, Zhu S, Cao B, Sun L, Li S, Li P, Zhang S, Dong S. Sun X, et al. Among authors: qiu jj. PLoS One. 2013 Oct 11;8(10):e77353. doi: 10.1371/journal.pone.0077353. eCollection 2013. PLoS One. 2013. PMID: 24146981 Free PMC article.

3

Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end.

Huang Y, Qiu J, Dong S, Redell MS, Poli V, Mancini MA, Tweardy DJ. Huang Y, et al. J Biol Chem. 2007 Nov 30;282(48):34958-67. doi: 10.1074/jbc.M704548200. Epub 2007 Sep 12. J Biol Chem. 2007. PMID: 17855361 Free article.

4

The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation.

Qiu J, Shi G, Jia Y, Li J, Wu M, Li J, Dong S, Wong J. Qiu J, et al. Cell Res. 2010 Aug;20(8):908-18. doi: 10.1038/cr.2010.81. Epub 2010 Jun 15. Cell Res. 2010. PMID: 20548336

5

The reduced and altered activities of PAX5 are linked to the protein-protein interaction motif (coiled-coil domain) of the PAX5-PML fusion protein in t(9;15)-associated acute lymphocytic leukemia.

Qiu JJ, Chu H, Lu X, Jiang X, Dong S. Qiu JJ, et al. Oncogene. 2011 Feb 24;30(8):967-77. doi: 10.1038/onc.2010.473. Epub 2010 Oct 25. Oncogene. 2011. PMID: 20972455

6

Critical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of NUP98-RARG leukemia.

Qiu JJ, Zeisig BB, Li S, Liu W, Chu H, Song Y, Giordano A, Schwaller J, Gronemeyer H, Dong S, So CW. Qiu JJ, et al. Leukemia. 2015 May;29(5):1153-62. doi: 10.1038/leu.2014.334. Epub 2014 Dec 16. Leukemia. 2015. PMID: 25510432

7

Aberrant chromatin remodeling by retinoic acid receptor alpha fusion proteins assessed at the single-cell level.

Qiu J, Huang Y, Chen G, Chen Z, Tweardy DJ, Dong S. Qiu J, et al. Mol Biol Cell. 2007 Oct;18(10):3941-51. doi: 10.1091/mbc.e07-03-0245. Epub 2007 Aug 1. Mol Biol Cell. 2007. PMID: 17671166 Free PMC article.

8

Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha.

Dong S, Stenoien DL, Qiu J, Mancini MA, Tweardy DJ. Dong S, et al. Mol Cell Biol. 2004 May;24(10):4465-75. doi: 10.1128/MCB.24.10.4465-4475.2004. Mol Cell Biol. 2004. PMID: 15121864 Free PMC article.

9

Leukemic transformation by the APL fusion protein PRKAR1A-RAR{alpha} critically depends on recruitment of RXR{alpha}.

Qiu JJ, Lu X, Zeisig BB, Ma Z, Cai X, Chen S, Gronemeyer H, Tweardy DJ, So CW, Dong S. Qiu JJ, et al. Blood. 2010 Jan 21;115(3):643-52. doi: 10.1182/blood-2009-07-232652. Epub 2009 Nov 17. Blood. 2010. PMID: 19965660 Free article.

10

Essential role for the dimerization domain of NuMA-RARalpha in its oncogenic activities and localization to NuMA sites within the nucleus.

Dong S, Qiu J, Stenoien DL, Brinkley WR, Mancini MA, Tweardy DJ. Dong S, et al. Oncogene. 2003 Feb 13;22(6):858-68. doi: 10.1038/sj.onc.1206182. Oncogene. 2003. PMID: 12584566

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