Dong S - Search Results

1

Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.

Liu Z, Yao Y, Kogiso M, Zheng B, Deng L, Qiu JJ, Dong S, Lv H, Gallo JM, Li XN, Song Y. Liu Z, et al. Among authors: dong s. J Med Chem. 2014 Oct 23;57(20):8307-18. doi: 10.1021/jm500660f. Epub 2014 Oct 1. J Med Chem. 2014. PMID: 25271760 Free PMC article.

2

Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L.

Anglin JL, Deng L, Yao Y, Cai G, Liu Z, Jiang H, Cheng G, Chen P, Dong S, Song Y. Anglin JL, et al. Among authors: dong s. J Med Chem. 2012 Sep 27;55(18):8066-74. doi: 10.1021/jm300917h. Epub 2012 Sep 6. J Med Chem. 2012. PMID: 22924785 Free PMC article.

3

Synthesis, Activity and Metabolic Stability of Non-Ribose Containing Inhibitors of Histone Methyltransferase DOT1L.

Deng L, Zhang L, Yao Y, Wang C, Redell MS, Dong S, Song Y. Deng L, et al. Among authors: dong s. Medchemcomm. 2013 May 1;4(5):822-826. doi: 10.1039/C3MD00021D. Medchemcomm. 2013. PMID: 23795283 Free PMC article.

4

Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.

Feng Z, Yao Y, Zhou C, Chen F, Wu F, Wei L, Liu W, Dong S, Redell M, Mo Q, Song Y. Feng Z, et al. Among authors: dong s. J Hematol Oncol. 2016 Mar 12;9:24. doi: 10.1186/s13045-016-0252-7. J Hematol Oncol. 2016. PMID: 26970896 Free PMC article.

5

Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end.

Huang Y, Qiu J, Dong S, Redell MS, Poli V, Mancini MA, Tweardy DJ. Huang Y, et al. Among authors: dong s. J Biol Chem. 2007 Nov 30;282(48):34958-67. doi: 10.1074/jbc.M704548200. Epub 2007 Sep 12. J Biol Chem. 2007. PMID: 17855361 Free article.

6

Oncogenic features of PHF8 histone demethylase in esophageal squamous cell carcinoma.

Sun X, Qiu JJ, Zhu S, Cao B, Sun L, Li S, Li P, Zhang S, Dong S. Sun X, et al. Among authors: dong s. PLoS One. 2013 Oct 11;8(10):e77353. doi: 10.1371/journal.pone.0077353. eCollection 2013. PLoS One. 2013. PMID: 24146981 Free PMC article.

7

The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation.

Qiu J, Shi G, Jia Y, Li J, Wu M, Li J, Dong S, Wong J. Qiu J, et al. Among authors: dong s. Cell Res. 2010 Aug;20(8):908-18. doi: 10.1038/cr.2010.81. Epub 2010 Jun 15. Cell Res. 2010. PMID: 20548336

8

Leukemic transformation by the APL fusion protein PRKAR1A-RAR{alpha} critically depends on recruitment of RXR{alpha}.

Qiu JJ, Lu X, Zeisig BB, Ma Z, Cai X, Chen S, Gronemeyer H, Tweardy DJ, So CW, Dong S. Qiu JJ, et al. Among authors: dong s. Blood. 2010 Jan 21;115(3):643-52. doi: 10.1182/blood-2009-07-232652. Epub 2009 Nov 17. Blood. 2010. PMID: 19965660 Free article.

9

Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha.

Dong S, Stenoien DL, Qiu J, Mancini MA, Tweardy DJ. Dong S, et al. Mol Cell Biol. 2004 May;24(10):4465-75. doi: 10.1128/MCB.24.10.4465-4475.2004. Mol Cell Biol. 2004. PMID: 15121864 Free PMC article.

10

Aberrant chromatin remodeling by retinoic acid receptor alpha fusion proteins assessed at the single-cell level.

Qiu J, Huang Y, Chen G, Chen Z, Tweardy DJ, Dong S. Qiu J, et al. Among authors: dong s. Mol Biol Cell. 2007 Oct;18(10):3941-51. doi: 10.1091/mbc.e07-03-0245. Epub 2007 Aug 1. Mol Biol Cell. 2007. PMID: 17671166 Free PMC article.

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