Thiyagarajan T - Search Results

1

Renal glycosphingolipid metabolism is dysfunctional in lupus nephritis.

Nowling TK, Mather AR, Thiyagarajan T, Hernández-Corbacho MJ, Powers TW, Jones EE, Snider AJ, Oates JC, Drake RR, Siskind LJ. Nowling TK, et al. Among authors: thiyagarajan t. J Am Soc Nephrol. 2015 Jun;26(6):1402-13. doi: 10.1681/ASN.2014050508. Epub 2014 Sep 30. J Am Soc Nephrol. 2015. PMID: 25270066 Free PMC article.

2

Reducing FLI1 levels in the MRL/lpr lupus mouse model impacts T cell function by modulating glycosphingolipid metabolism.

Richard EM, Thiyagarajan T, Bunni MA, Basher F, Roddy PO, Siskind LJ, Nietert PJ, Nowling TK. Richard EM, et al. Among authors: thiyagarajan t. PLoS One. 2013 Sep 10;8(9):e75175. doi: 10.1371/journal.pone.0075175. eCollection 2013. PLoS One. 2013. PMID: 24040398 Free PMC article.

3

FLI1 Levels Impact CXCR3 Expression and Renal Infiltration of T Cells and Renal Glycosphingolipid Metabolism in the MRL/lpr Lupus Mouse Strain.

Sundararaj KP, Thiyagarajan T, Molano I, Basher F, Powers TW, Drake RR, Nowling TK. Sundararaj KP, et al. Among authors: thiyagarajan t. J Immunol. 2015 Dec 15;195(12):5551-60. doi: 10.4049/jimmunol.1500961. Epub 2015 Nov 4. J Immunol. 2015. PMID: 26538397 Free PMC article.

4

Targeting glycosphingolipid metabolism as a potential therapeutic approach for treating disease in female MRL/lpr lupus mice.

Nowling TK, Rodgers J, Thiyagarajan T, Wolf B, Bruner E, Sundararaj K, Molano I, Gilkeson G. Nowling TK, et al. Among authors: thiyagarajan t. PLoS One. 2020 Mar 18;15(3):e0230499. doi: 10.1371/journal.pone.0230499. eCollection 2020. PLoS One. 2020. PMID: 32187230 Free PMC article.

5

beta-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes.

Mani SK, Egan EA, Addy BK, Grimm M, Kasiganesan H, Thiyagarajan T, Renaud L, Brown JH, Kern CB, Menick DR. Mani SK, et al. Among authors: thiyagarajan t. J Mol Cell Cardiol. 2010 Feb;48(2):342-51. doi: 10.1016/j.yjmcc.2009.11.007. Epub 2009 Nov 27. J Mol Cell Cardiol. 2010. PMID: 19945464 Free PMC article.

6

Pyrazol-1-yl-propanamides as SARD and Pan-Antagonists for the Treatment of Enzalutamide-Resistant Prostate Cancer.

He Y, Hwang DJ, Ponnusamy S, Thiyagarajan T, Mohler ML, Narayanan R, Miller DD. He Y, et al. Among authors: thiyagarajan t. J Med Chem. 2020 Nov 12;63(21):12642-12665. doi: 10.1021/acs.jmedchem.0c00943. Epub 2020 Oct 23. J Med Chem. 2020. PMID: 33095584 Free PMC article.

7

Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes.

Chandrasekaran S, Peterson RE, Mani SK, Addy B, Buchholz AL, Xu L, Thiyagarajan T, Kasiganesan H, Kern CB, Menick DR. Chandrasekaran S, et al. Among authors: thiyagarajan t. FASEB J. 2009 Nov;23(11):3851-64. doi: 10.1096/fj.09-132415. Epub 2009 Jul 28. FASEB J. 2009. PMID: 19638401 Free PMC article.

8

Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer.

Ponnusamy S, Coss CC, Thiyagarajan T, Watts K, Hwang DJ, He Y, Selth LA, McEwan IJ, Duke CB, Pagadala J, Singh G, Wake RW, Ledbetter C, Tilley WD, Moldoveanu T, Dalton JT, Miller DD, Narayanan R. Ponnusamy S, et al. Among authors: thiyagarajan t. Cancer Res. 2017 Nov 15;77(22):6282-6298. doi: 10.1158/0008-5472.CAN-17-0976. Epub 2017 Oct 4. Cancer Res. 2017. PMID: 28978635 Free PMC article.

9

New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity.

Hwang DJ, He Y, Ponnusamy S, Mohler ML, Thiyagarajan T, McEwan IJ, Narayanan R, Miller DD. Hwang DJ, et al. Among authors: thiyagarajan t. J Med Chem. 2019 Jan 24;62(2):491-511. doi: 10.1021/acs.jmedchem.8b00973. Epub 2018 Dec 26. J Med Chem. 2019. PMID: 30525603

10

Orally Bioavailable Androgen Receptor Degrader, Potential Next-Generation Therapeutic for Enzalutamide-Resistant Prostate Cancer.

Ponnusamy S, He Y, Hwang DJ, Thiyagarajan T, Houtman R, Bocharova V, Sumpter BG, Fernandez E, Johnson D, Du Z, Pfeffer LM, Getzenberg RH, McEwan IJ, Miller DD, Narayanan R. Ponnusamy S, et al. Among authors: thiyagarajan t. Clin Cancer Res. 2019 Nov 15;25(22):6764-6780. doi: 10.1158/1078-0432.CCR-19-1458. Epub 2019 Sep 3. Clin Cancer Res. 2019. PMID: 31481513

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