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A prospective randomized exploratory study comparing the efficacy of once-daily topical 0.5% 5-fluorouracil in combination with 10.0% salicylic acid (5-FU/SA) vs. cryosurgery for the treatment of hyperkeratotic actinic keratosis.
Simon JC, Dominicus R, Karl L, Rodríguez R, Willers C, Dirschka T. Simon JC, et al. Among authors: dominicus r. J Eur Acad Dermatol Venereol. 2015 May;29(5):881-9. doi: 10.1111/jdv.12702. Epub 2014 Sep 25. J Eur Acad Dermatol Venereol. 2015. PMID: 25257941 Free article. Clinical Trial.
Optimization of photodynamic therapy with a novel self-adhesive 5-aminolaevulinic acid patch: results of two randomized controlled phase III studies.
Hauschild A, Stockfleth E, Popp G, Borrosch F, Brüning H, Dominicus R, Mensing H, Reinhold U, Reich K, Moor AC, Stocker M, Ortland C, Brunnert M, Szeimies RM. Hauschild A, et al. Among authors: dominicus r. Br J Dermatol. 2009 May;160(5):1066-74. doi: 10.1111/j.1365-2133.2009.09040.x. Epub 2009 Feb 16. Br J Dermatol. 2009. PMID: 19222455 Clinical Trial.
Long-term follow-up of photodynamic therapy with a self-adhesive 5-aminolaevulinic acid patch: 12 months data.
Szeimies RM, Stockfleth E, Popp G, Borrosch F, Brüning H, Dominicus R, Mensing H, Reinhold U, Reich K, Moor AC, Stocker M, Ortland C, Brunnert M, Hauschild A. Szeimies RM, et al. Among authors: dominicus r. Br J Dermatol. 2010 Feb 1;162(2):410-4. doi: 10.1111/j.1365-2133.2009.09377.x. Epub 2009 Jun 30. Br J Dermatol. 2010. PMID: 19804593 Clinical Trial.
Photodynamic therapy with BF-200 ALA for the treatment of actinic keratosis: results of a multicentre, randomized, observer-blind phase III study in comparison with a registered methyl-5-aminolaevulinate cream and placebo.
Dirschka T, Radny P, Dominicus R, Mensing H, Brüning H, Jenne L, Karl L, Sebastian M, Oster-Schmidt C, Klövekorn W, Reinhold U, Tanner M, Gröne D, Deichmann M, Simon M, Hübinger F, Hofbauer G, Krähn-Senftleben G, Borrosch F, Reich K, Berking C, Wolf P, Lehmann P, Moers-Carpi M, Hönigsmann H, Wernicke-Panten K, Helwig C, Foguet M, Schmitz B, Lübbert H, Szeimies RM; AK-CT002 Study Group. Dirschka T, et al. Among authors: dominicus r. Br J Dermatol. 2012 Jan;166(1):137-46. doi: 10.1111/j.1365-2133.2011.10613.x. Epub 2011 Dec 21. Br J Dermatol. 2012. PMID: 21910711 Clinical Trial.
Randomized, double-blind, placebo-controlled study of safety and efficacy of miltefosine in antihistamine-resistant chronic spontaneous urticaria.
Magerl M, Rother M, Bieber T, Biedermann T, Brasch J, Dominicus R, Hunzelmann N, Jakob T, Mahler V, Popp G, Schäkel K, Schlingensiepen R, Schmitt J, Siebenhaar F, Simon JC, Staubach P, Wedi B, Weidner C, Maurer M. Magerl M, et al. Among authors: dominicus r. J Eur Acad Dermatol Venereol. 2013 Mar;27(3):e363-9. doi: 10.1111/j.1468-3083.2012.04689.x. Epub 2012 Aug 29. J Eur Acad Dermatol Venereol. 2013. PMID: 22928719 Clinical Trial.
Long-term (6 and 12 months) follow-up of two prospective, randomized, controlled phase III trials of photodynamic therapy with BF-200 ALA and methyl aminolaevulinate for the treatment of actinic keratosis.
Dirschka T, Radny P, Dominicus R, Mensing H, Brüning H, Jenne L, Karl L, Sebastian M, Oster-Schmidt C, Klövekorn W, Reinhold U, Tanner M, Gröne D, Deichmann M, Simon M, Hübinger F, Hofbauer G, Krähn-Senftleben G, Borrosch F, Reich K, Berking C, Wolf P, Lehmann P, Moers-Carpi M, Hönigsmann H, Wernicke-Panten K, Hahn S, Pabst G, Voss D, Foguet M, Schmitz B, Lübbert H, Szeimies RM; AK-CT002 Study Group; AK-CT003 Study Group. Dirschka T, et al. Among authors: dominicus r. Br J Dermatol. 2013 Apr;168(4):825-36. doi: 10.1111/bjd.12158. Br J Dermatol. 2013. PMID: 23252768 Free PMC article. Clinical Trial.
Efficacy and Safety of 5-Fluorouracil 0.5%/Salicylic Acid 10% in the Field-Directed Treatment of Actinic Keratosis: A Phase III, Randomized, Double-Blind, Vehicle-Controlled Trial.
Stockfleth E, von Kiedrowski R, Dominicus R, Ryan J, Ellery A, Falqués M, Ivanoff N, Azeredo RR. Stockfleth E, et al. Among authors: dominicus r. Dermatol Ther (Heidelb). 2017 Mar;7(1):81-96. doi: 10.1007/s13555-016-0161-2. Epub 2016 Dec 19. Dermatol Ther (Heidelb). 2017. PMID: 27995485 Free PMC article.
A randomized, multinational, noninferiority, phase III trial to evaluate the safety and efficacy of BF-200 aminolaevulinic acid gel vs. methyl aminolaevulinate cream in the treatment of nonaggressive basal cell carcinoma with photodynamic therapy.
Morton CA, Dominicus R, Radny P, Dirschka T, Hauschild A, Reinhold U, Aschoff R, Ulrich M, Keohane S, Ekanayake-Bohlig S, Ibbotson S, Ostendorf R, Berking C, Gröne D, Schulze HJ, Ockenfels HM, Jasnoch V, Kurzen H, Sebastian M, Stege H, Staubach P, Gupta G, Hübinger F, Ziabreva I, Schmitz B, Gertzmann A, Lübbert H, Szeimies RM. Morton CA, et al. Among authors: dominicus r. Br J Dermatol. 2018 Aug;179(2):309-319. doi: 10.1111/bjd.16441. Epub 2018 May 16. Br J Dermatol. 2018. PMID: 29432644 Free article. Clinical Trial.
A randomized, intraindividual, non-inferiority, Phase III study comparing daylight photodynamic therapy with BF-200 ALA gel and MAL cream for the treatment of actinic keratosis.
Dirschka T, Ekanayake-Bohlig S, Dominicus R, Aschoff R, Herrera-Ceballos E, Botella-Estrada R, Hunfeld A, Kremser M, Schmitz B, Lübbert H, Puig S. Dirschka T, et al. Among authors: dominicus r. J Eur Acad Dermatol Venereol. 2019 Feb;33(2):288-297. doi: 10.1111/jdv.15185. Epub 2018 Aug 14. J Eur Acad Dermatol Venereol. 2019. PMID: 30022544 Free PMC article. Clinical Trial.
Methyl aminolevulinate daylight photodynamic therapy applied at home for non-hyperkeratotic actinic keratosis of the face or scalp: an open, interventional study conducted in Germany.
Karrer S, Aschoff RAG, Dominicus R, Krähn-Senftleben G, Gauglitz GG, Zarzour A, Kerrouche N, Chavda R, Szeimies RM. Karrer S, et al. Among authors: dominicus r. J Eur Acad Dermatol Venereol. 2019 Apr;33(4):661-666. doi: 10.1111/jdv.15422. Epub 2019 Feb 22. J Eur Acad Dermatol Venereol. 2019. PMID: 30633376
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