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Page 1
Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema.
Ramnath NW, van de Luijtgaarden KM, van der Pluijm I, van Nimwegen M, van Heijningen PM, Swagemakers SM, van Thiel BS, Ridwan RY, van Vliet N, Vermeij M, Hawinkels LJ, de Munck A, Dzyubachyk O, Meijering E, van der Spek P, Rottier R, Yanagisawa H, Hendriks RW, Kanaar R, Rouwet EV, Kleinjan A, Essers J. Ramnath NW, et al. Among authors: van thiel bs, van de luijtgaarden km, van der pluijm i, van heijningen pm, van nimwegen m, van vliet n, van der spek p. PLoS One. 2014 Sep 25;9(9):e106054. doi: 10.1371/journal.pone.0106054. eCollection 2014. PLoS One. 2014. PMID: 25255451 Free PMC article.
AT1-receptor blockade, but not renin inhibition, reduces aneurysm growth and cardiac failure in fibulin-4 mice.
Te Riet L, van Deel ED, van Thiel BS, Moltzer E, van Vliet N, Ridwan Y, van Veghel R, van Heijningen PM, Robertus JL, Garrelds IM, Vermeij M, van der Pluijm I, Danser AH, Essers J. Te Riet L, et al. Among authors: van veghel r, van thiel bs, van heijningen pm, van der pluijm i, van vliet n, van deel ed. J Hypertens. 2016 Apr;34(4):654-65. doi: 10.1097/HJH.0000000000000845. J Hypertens. 2016. PMID: 26828783
Defective Connective Tissue Remodeling in Smad3 Mice Leads to Accelerated Aneurysmal Growth Through Disturbed Downstream TGF-β Signaling.
van der Pluijm I, van Vliet N, von der Thusen JH, Robertus JL, Ridwan Y, van Heijningen PM, van Thiel BS, Vermeij M, Hoeks SE, Buijs-Offerman RMGB, Verhagen HJM, Kanaar R, Bertoli-Avella AM, Essers J. van der Pluijm I, et al. Among authors: van thiel bs, van heijningen pm, van vliet n. EBioMedicine. 2016 Oct;12:280-294. doi: 10.1016/j.ebiom.2016.09.006. Epub 2016 Sep 10. EBioMedicine. 2016. PMID: 27688095 Free PMC article.
Aortic microcalcification is associated with elastin fragmentation in Marfan syndrome.
Wanga S, Hibender S, Ridwan Y, van Roomen C, Vos M, van der Made I, van Vliet N, Franken R, van Riel LA, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, Essers J, de Waard V. Wanga S, et al. Among authors: van der made i, van riel la, van roomen c, van vliet n. J Pathol. 2017 Nov;243(3):294-306. doi: 10.1002/path.4949. Epub 2017 Sep 21. J Pathol. 2017. PMID: 28727149 Free article.
Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.
van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J. van der Pluijm I, et al. Among authors: van heijningen pm, van der linden r, van vliet n. Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150. Cardiovasc Res. 2018. PMID: 29931197 Free PMC article.
Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling.
Burger J, van Vliet N, van Heijningen P, Kumra H, Kremers GJ, Alves M, van Cappellen G, Yanagisawa H, Reinhardt DP, Kanaar R, van der Pluijm I, Essers J. Burger J, et al. Among authors: van cappellen g, van der pluijm i, van vliet n, van heijningen p. Cell Signal. 2019 Jun;58:65-78. doi: 10.1016/j.cellsig.2019.02.008. Epub 2019 Mar 4. Cell Signal. 2019. PMID: 30844428 Free article.
HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.
Brandsma I, Sato K, van Rossum-Fikkert SE, van Vliet N, Sleddens E, Reuter M, Odijk H, van den Tempel N, Dekkers DHW, Bezstarosti K, Demmers JAA, Maas A, Lebbink J, Wyman C, Essers J, van Gent DC, Baarends WM, Knipscheer P, Kanaar R, Zelensky AN. Brandsma I, et al. Among authors: van gent dc, van rossum fikkert se, van den tempel n, van vliet n. Cell Rep. 2019 Jun 25;27(13):3790-3798.e7. doi: 10.1016/j.celrep.2019.05.096. Cell Rep. 2019. PMID: 31242413 Free article.
Molecular phenotyping and functional assessment of smooth muscle-like cells with pathogenic variants in aneurysm genes ACTA2, MYH11, SMAD3 and FBN1.
Burger J, Bogunovic N, de Wagenaar NP, Liu H, van Vliet N, IJpma A, Maugeri A, Micha D, Verhagen HJM, Ten Hagen TLM, Majoor-Krakauer D, van der Pluijm I, Essers J, Yeung KK. Burger J, et al. Among authors: van der pluijm i, van vliet n. Hum Mol Genet. 2021 Nov 16;30(23):2286-2299. doi: 10.1093/hmg/ddab190. Hum Mol Genet. 2021. PMID: 34244757 Free PMC article.
Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response.
van der Linden J, Stefens SJM, Heredia-Genestar JM, Ridwan Y, Brandt RMC, van Vliet N, de Beer I, van Thiel BS, Steen H, Cheng C, Roks AJM, Danser AHJ, Essers J, van der Pluijm I. van der Linden J, et al. Among authors: van vliet n. Aging Cell. 2024 May;23(5):e14126. doi: 10.1111/acel.14126. Epub 2024 Mar 7. Aging Cell. 2024. PMID: 38451018 Free PMC article.
52 results