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MEK inhibitor for gastric cancer with MEK1 gene mutations.
Sogabe S, Togashi Y, Kato H, Kogita A, Mizukami T, Sakamoto Y, Banno E, Terashima M, Hayashi H, de Velasco MA, Sakai K, Fujita Y, Tomida S, Yasuda T, Takeyama Y, Okuno K, Nishio K. Sogabe S, et al. Among authors: de velasco ma. Mol Cancer Ther. 2014 Dec;13(12):3098-106. doi: 10.1158/1535-7163.MCT-14-0429. Epub 2014 Sep 24. Mol Cancer Ther. 2014. PMID: 25253779
FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth.
Kaneda H, Arao T, Tanaka K, Tamura D, Aomatsu K, Kudo K, Sakai K, De Velasco MA, Matsumoto K, Fujita Y, Yamada Y, Tsurutani J, Okamoto I, Nakagawa K, Nishio K. Kaneda H, et al. Among authors: de velasco ma. Cancer Res. 2010 Mar 1;70(5):2053-63. doi: 10.1158/0008-5472.CAN-09-2161. Epub 2010 Feb 9. Cancer Res. 2010. PMID: 20145154
Antitumor activity of BIBF 1120, a triple angiokinase inhibitor, and use of VEGFR2+pTyr+ peripheral blood leukocytes as a pharmacodynamic biomarker in vivo.
Kudo K, Arao T, Tanaka K, Nagai T, Furuta K, Sakai K, Kaneda H, Matsumoto K, Tamura D, Aomatsu K, De Velasco MA, Fujita Y, Saijo N, Kudo M, Nishio K. Kudo K, et al. Among authors: de velasco ma. Clin Cancer Res. 2011 Mar 15;17(6):1373-81. doi: 10.1158/1078-0432.CCR-09-2755. Epub 2010 Dec 3. Clin Cancer Res. 2011. PMID: 21131553
Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer.
Kaneda H, Arao T, Matsumoto K, De Velasco MA, Tamura D, Aomatsu K, Kudo K, Sakai K, Nagai T, Fujita Y, Tanaka K, Yanagihara K, Yamada Y, Okamoto I, Nakagawa K, Nishio K. Kaneda H, et al. Among authors: de velasco ma. Br J Cancer. 2011 Oct 11;105(8):1210-7. doi: 10.1038/bjc.2011.348. Epub 2011 Sep 6. Br J Cancer. 2011. PMID: 21897392 Free PMC article.
Slug increases sensitivity to tubulin-binding agents via the downregulation of βIII and βIVa-tubulin in lung cancer cells.
Tamura D, Arao T, Nagai T, Kaneda H, Aomatsu K, Fujita Y, Matsumoto K, De Velasco MA, Kato H, Hayashi H, Yoshida S, Kimura H, Maniwa Y, Nishio W, Sakai Y, Ohbayashi C, Kotani Y, Nishimura Y, Nishio K. Tamura D, et al. Among authors: de velasco ma. Cancer Med. 2013 Apr;2(2):144-54. doi: 10.1002/cam4.68. Epub 2013 Mar 1. Cancer Med. 2013. PMID: 23634282 Free PMC article.
Overexpression of heparan sulfate 6-O-sulfotransferase-2 in colorectal cancer.
Hatabe S, Kimura H, Arao T, Kato H, Hayashi H, Nagai T, Matsumoto K, DE Velasco M, Fujita Y, Yamanouchi G, Fukushima M, Yamada Y, Ito A, Okuno K, Nishio K. Hatabe S, et al. Mol Clin Oncol. 2013 Sep;1(5):845-850. doi: 10.3892/mco.2013.151. Epub 2013 Jul 23. Mol Clin Oncol. 2013. PMID: 24649258 Free PMC article.
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