McPherson SA - Search Results

1

Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridge.

Aldred KJ, Breland EJ, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N. Aldred KJ, et al. Among authors: mcpherson sa. Antimicrob Agents Chemother. 2014 Dec;58(12):7182-7. doi: 10.1128/AAC.03734-14. Epub 2014 Sep 22. Antimicrob Agents Chemother. 2014. PMID: 25246407 Free PMC article.

2

Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.

Aldred KJ, McPherson SA, Wang P, Kerns RJ, Graves DE, Turnbough CL Jr, Osheroff N. Aldred KJ, et al. Among authors: mcpherson sa. Biochemistry. 2012 Jan 10;51(1):370-81. doi: 10.1021/bi2013905. Epub 2011 Dec 16. Biochemistry. 2012. PMID: 22126453 Free PMC article.

3

Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance.

Aldred KJ, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N. Aldred KJ, et al. Among authors: mcpherson sa. Nucleic Acids Res. 2013 Apr;41(8):4628-39. doi: 10.1093/nar/gkt124. Epub 2013 Mar 4. Nucleic Acids Res. 2013. PMID: 23460203 Free PMC article.

4

Overcoming target-mediated quinolone resistance in topoisomerase IV by introducing metal-ion-independent drug-enzyme interactions.

Aldred KJ, Schwanz HA, Li G, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N. Aldred KJ, et al. Among authors: mcpherson sa. ACS Chem Biol. 2013 Dec 20;8(12):2660-8. doi: 10.1021/cb400592n. Epub 2013 Sep 30. ACS Chem Biol. 2013. PMID: 24047414 Free PMC article.

5

Activity of quinolone CP-115,955 against bacterial and human type II topoisomerases is mediated by different interactions.

Aldred KJ, Schwanz HA, Li G, Williamson BH, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N. Aldred KJ, et al. Among authors: mcpherson sa. Biochemistry. 2015 Feb 10;54(5):1278-86. doi: 10.1021/bi501073v. Epub 2015 Jan 23. Biochemistry. 2015. PMID: 25586498 Free PMC article.

6

Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance.

Ashley RE, Lindsey RH Jr, McPherson SA, Turnbough CL Jr, Kerns RJ, Osheroff N. Ashley RE, et al. Among authors: mcpherson sa. Biochemistry. 2017 Aug 15;56(32):4191-4200. doi: 10.1021/acs.biochem.7b00203. Epub 2017 Aug 1. Biochemistry. 2017. PMID: 28708938 Free PMC article.

7

Activities of gyrase and topoisomerase IV on positively supercoiled DNA.

Ashley RE, Dittmore A, McPherson SA, Turnbough CL Jr, Neuman KC, Osheroff N. Ashley RE, et al. Among authors: mcpherson sa. Nucleic Acids Res. 2017 Sep 19;45(16):9611-9624. doi: 10.1093/nar/gkx649. Nucleic Acids Res. 2017. PMID: 28934496 Free PMC article.

8

Anthrose biosynthetic operon of Bacillus anthracis.

Dong S, McPherson SA, Tan L, Chesnokova ON, Turnbough CL Jr, Pritchard DG. Dong S, et al. Among authors: mcpherson sa. J Bacteriol. 2008 Apr;190(7):2350-9. doi: 10.1128/JB.01899-07. Epub 2008 Feb 1. J Bacteriol. 2008. PMID: 18245286 Free PMC article.

9

The spore-specific alanine racemase of Bacillus anthracis and its role in suppressing germination during spore development.

Chesnokova ON, McPherson SA, Steichen CT, Turnbough CL Jr. Chesnokova ON, et al. Among authors: mcpherson sa. J Bacteriol. 2009 Feb;191(4):1303-10. doi: 10.1128/JB.01098-08. Epub 2008 Dec 12. J Bacteriol. 2009. PMID: 19074397 Free PMC article.

10

ExsB, an unusually highly phosphorylated protein required for the stable attachment of the exosporium of Bacillus anthracis.

McPherson SA, Li M, Kearney JF, Turnbough CL Jr. McPherson SA, et al. Mol Microbiol. 2010 Jun;76(6):1527-38. doi: 10.1111/j.1365-2958.2010.07182.x. Epub 2010 Apr 23. Mol Microbiol. 2010. PMID: 20444088 Free PMC article.

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