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Page 1
Synthesis and evaluation of new antitumor 3-aminomethyl-4,11-dihydroxynaphtho[2,3-f]indole-5,10-diones.
Shchekotikhin AE, Glazunova VA, Dezhenkova LG, Luzikov YN, Buyanov VN, Treshalina HM, Lesnaya NA, Romanenko VI, Kaluzhny DN, Balzarini J, Agama K, Pommier Y, Shtil AA, Preobrazhenskaya MN. Shchekotikhin AE, et al. Among authors: shtil aa. Eur J Med Chem. 2014 Oct 30;86:797-805. doi: 10.1016/j.ejmech.2014.09.021. Epub 2014 Sep 8. Eur J Med Chem. 2014. PMID: 25244612
Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-diones.
Shchekotikhin AE, Glazunova VA, Dezhenkova LG, Luzikov YN, Sinkevich YB, Kovalenko LV, Buyanov VN, Balzarini J, Huang FC, Lin JJ, Huang HS, Shtil AA, Preobrazhenskaya MN. Shchekotikhin AE, et al. Among authors: shtil aa. Bioorg Med Chem. 2009 Mar 1;17(5):1861-9. doi: 10.1016/j.bmc.2009.01.047. Epub 2009 Jan 27. Bioorg Med Chem. 2009. PMID: 19208482
Reaction of the antitumor antibiotic olivomycin I with aryl diazonium salts. Synthesis, cytotoxic and antiretroviral potency of 5-aryldiazenyl-6-O-deglycosyl derivatives of olivomycin I.
Tevyashova AN, Olsufyeva EN, Turchin KF, Balzarini J, Bykov EE, Dezhenkova LG, Shtil AA, Preobrazhenskaya MN. Tevyashova AN, et al. Among authors: shtil aa. Bioorg Med Chem. 2009 Jul 15;17(14):4961-7. doi: 10.1016/j.bmc.2009.05.076. Epub 2009 Jun 6. Bioorg Med Chem. 2009. PMID: 19535252
Modification of olivomycin A at the side chain of the aglycon yields the derivative with perspective antitumor characteristics.
Tevyashova AN, Shtil AA, Olsufyeva EN, Luzikov YN, Reznikova MI, Dezhenkova LG, Isakova EB, Bukhman VM, Durandin NA, Vinogradov AM, Kuzmin VA, Preobrazhenskaya MN. Tevyashova AN, et al. Among authors: shtil aa. Bioorg Med Chem. 2011 Dec 15;19(24):7387-93. doi: 10.1016/j.bmc.2011.10.055. Epub 2011 Oct 25. Bioorg Med Chem. 2011. PMID: 22088308
Novel multi-targeting anthra[2,3-b]thiophene-5,10-diones with guanidine-containing side chains: interaction with telomeric G-quadruplex, inhibition of telomerase and topoisomerase I and cytotoxic properties.
Ilyinsky NS, Shchyolkina AK, Borisova OF, Mamaeva OK, Zvereva MI, Azhibek DM, Livshits MA, Mitkevich VA, Balzarini J, Sinkevich YB, Luzikov YN, Dezhenkova LG, Kolotova ES, Shtil AA, Shchekotikhin AE, Kaluzhny DN. Ilyinsky NS, et al. Among authors: shtil aa. Eur J Med Chem. 2014 Oct 6;85:605-14. doi: 10.1016/j.ejmech.2014.08.030. Epub 2014 Aug 8. Eur J Med Chem. 2014. PMID: 25127152
208 results