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PI3KCA plays a major role in multiple myeloma and its inhibition with BYL719 decreases proliferation, synergizes with other therapies and overcomes stroma-induced resistance.
Azab F, Vali S, Abraham J, Potter N, Muz B, de la Puente P, Fiala M, Paasch J, Sultana Z, Tyagi A, Abbasi T, Vij R, Azab AK. Azab F, et al. Among authors: muz b. Br J Haematol. 2014 Apr;165(1):89-101. doi: 10.1111/bjh.12734. Epub 2014 Jan 9. Br J Haematol. 2014. PMID: 24405121 Free article.
Molecularly targeted therapies in multiple myeloma.
de la Puente P, Muz B, Azab F, Luderer M, Azab AK. de la Puente P, et al. Among authors: muz b. Leuk Res Treatment. 2014;2014:976567. doi: 10.1155/2014/976567. Epub 2014 Apr 16. Leuk Res Treatment. 2014. PMID: 24829804 Free PMC article. Review.
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