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Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.
Yamashita A, Morioka M, Kishi H, Kimura T, Yahara Y, Okada M, Fujita K, Sawai H, Ikegawa S, Tsumaki N. Yamashita A, et al. Among authors: kimura t. Nature. 2014 Sep 25;513(7519):507-11. doi: 10.1038/nature13775. Epub 2014 Sep 17. Nature. 2014. PMID: 25231866
An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice.
Kimura T, Bosakova M, Nonaka Y, Hruba E, Yasuda K, Futakawa S, Kubota T, Fafilek B, Gregor T, Abraham SP, Gomolkova R, Belaskova S, Pesl M, Csukasi F, Duran I, Fujiwara M, Kavkova M, Zikmund T, Kaiser J, Buchtova M, Krakow D, Nakamura Y, Ozono K, Krejci P. Kimura T, et al. Sci Transl Med. 2021 May 5;13(592):eaba4226. doi: 10.1126/scitranslmed.aba4226. Sci Transl Med. 2021. PMID: 33952673
The structural basis for receptor recognition of human interleukin-18.
Tsutsumi N, Kimura T, Arita K, Ariyoshi M, Ohnishi H, Yamamoto T, Zuo X, Maenaka K, Park EY, Kondo N, Shirakawa M, Tochio H, Kato Z. Tsutsumi N, et al. Among authors: kimura t. Nat Commun. 2014 Dec 15;5:5340. doi: 10.1038/ncomms6340. Nat Commun. 2014. PMID: 25500532 Free PMC article.
Gradient-based parameter optimization method to determine membrane ionic current composition in human induced pluripotent stem cell-derived cardiomyocytes.
Kohjitani H, Koda S, Himeno Y, Makiyama T, Yamamoto Y, Yoshinaga D, Wuriyanghai Y, Kashiwa A, Toyoda F, Zhang Y, Amano A, Noma A, Kimura T. Kohjitani H, et al. Among authors: kimura t. Sci Rep. 2022 Nov 9;12(1):19110. doi: 10.1038/s41598-022-23398-0. Sci Rep. 2022. PMID: 36351955 Free PMC article. Clinical Trial.
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