Ye N - Search Results

1

ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: synthesis of dihydropyran-fused diterpenoids.

Ding C, Wang L, Chen H, Wild C, Ye N, Ding Y, Wang T, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: ye n. Org Biomol Chem. 2014 Nov 14;12(42):8442-52. doi: 10.1039/c4ob01040j. Org Biomol Chem. 2014. PMID: 25225052 Free PMC article.

2

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Ye N, Ester CD, Xiong A, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: ye n. J Med Chem. 2013 Nov 14;56(21):8814-25. doi: 10.1021/jm401248x. Epub 2013 Oct 31. J Med Chem. 2013. PMID: 24128046 Free PMC article.

3

Discovery and development of natural product oridonin-inspired anticancer agents.

Ding Y, Ding C, Ye N, Liu Z, Wold EA, Chen H, Wild C, Shen Q, Zhou J. Ding Y, et al. Among authors: ye n. Eur J Med Chem. 2016 Oct 21;122:102-117. doi: 10.1016/j.ejmech.2016.06.015. Epub 2016 Jun 13. Eur J Med Chem. 2016. PMID: 27344488 Free PMC article. Review.

4

Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads.

Ding Y, Li D, Ding C, Wang P, Liu Z, Wold EA, Ye N, Chen H, White MA, Shen Q, Zhou J. Ding Y, et al. Among authors: ye n. J Med Chem. 2018 Apr 12;61(7):2737-2752. doi: 10.1021/acs.jmedchem.7b01514. Epub 2018 Mar 20. J Med Chem. 2018. PMID: 29528645 Free PMC article.

5

Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).

Chen H, Wild C, Zhou X, Ye N, Cheng X, Zhou J. Chen H, et al. Among authors: ye n. J Med Chem. 2014 May 8;57(9):3651-65. doi: 10.1021/jm401425e. Epub 2013 Nov 27. J Med Chem. 2014. PMID: 24256330 Free PMC article. Review.

6

Small molecule inhibitors targeting activator protein 1 (AP-1).

Ye N, Ding Y, Wild C, Shen Q, Zhou J. Ye N, et al. J Med Chem. 2014 Aug 28;57(16):6930-48. doi: 10.1021/jm5004733. Epub 2014 May 27. J Med Chem. 2014. PMID: 24831826 Free PMC article.

7

Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3).

Chen H, Yang Z, Ding C, Xiong A, Wild C, Wang L, Ye N, Cai G, Flores RM, Ding Y, Shen Q, Zhou J. Chen H, et al. Among authors: ye n. Eur J Med Chem. 2014 Jul 23;82:195-203. doi: 10.1016/j.ejmech.2014.05.049. Epub 2014 May 22. Eur J Med Chem. 2014. PMID: 24904966 Free PMC article.

8

Direct Activation of Bax Protein for Cancer Therapy.

Liu Z, Ding Y, Ye N, Wild C, Chen H, Zhou J. Liu Z, et al. Among authors: ye n. Med Res Rev. 2016 Mar;36(2):313-41. doi: 10.1002/med.21379. Epub 2015 Sep 23. Med Res Rev. 2016. PMID: 26395559 Free PMC article. Review.

9

KRAS - An Evolving Cancer Target.

Ye N, Zhou J. Ye N, et al. Austin J Cancer Clin Res. 2014;1(1):1004. Austin J Cancer Clin Res. 2014. PMID: 27642639 Free PMC article. No abstract available.

10

Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer.

Kuang Y, Ye N, Kyani A, Ljungman M, Paulsen M, Chen H, Zhou M, Wild C, Chen H, Zhou J, Neamati N. Kuang Y, et al. Among authors: ye n. J Med Chem. 2022 Apr 28;65(8):6133-6156. doi: 10.1021/acs.jmedchem.1c02207. Epub 2022 Apr 19. J Med Chem. 2022. PMID: 35439009 Free PMC article.

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