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911 results

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Page 1
Improving on nature: making a cyclic heptapeptide orally bioavailable.
Nielsen DS, Hoang HN, Lohman RJ, Hill TA, Lucke AJ, Craik DJ, Edmonds DJ, Griffith DA, Rotter CJ, Ruggeri RB, Price DA, Liras S, Fairlie DP. Nielsen DS, et al. Among authors: price da. Angew Chem Int Ed Engl. 2014 Nov 3;53(45):12059-63. doi: 10.1002/anie.201405364. Epub 2014 Sep 12. Angew Chem Int Ed Engl. 2014. PMID: 25219505
Comparative α-helicity of cyclic pentapeptides in water.
de Araujo AD, Hoang HN, Kok WM, Diness F, Gupta P, Hill TA, Driver RW, Price DA, Liras S, Fairlie DP. de Araujo AD, et al. Among authors: price da. Angew Chem Int Ed Engl. 2014 Jul 1;53(27):6965-9. doi: 10.1002/anie.201310245. Epub 2014 May 14. Angew Chem Int Ed Engl. 2014. PMID: 24828311
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed.
Hill TA, Lohman RJ, Hoang HN, Nielsen DS, Scully CC, Kok WM, Liu L, Lucke AJ, Stoermer MJ, Schroeder CI, Chaousis S, Colless B, Bernhardt PV, Edmonds DJ, Griffith DA, Rotter CJ, Ruggeri RB, Price DA, Liras S, Craik DJ, Fairlie DP. Hill TA, et al. Among authors: price da. ACS Med Chem Lett. 2014 Aug 4;5(10):1148-51. doi: 10.1021/ml5002823. eCollection 2014 Oct 9. ACS Med Chem Lett. 2014. PMID: 25313329 Free PMC article.
Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.
Hoang HN, Song K, Hill TA, Derksen DR, Edmonds DJ, Kok WM, Limberakis C, Liras S, Loria PM, Mascitti V, Mathiowetz AM, Mitchell JM, Piotrowski DW, Price DA, Stanton RV, Suen JY, Withka JM, Griffith DA, Fairlie DP. Hoang HN, et al. Among authors: price da. J Med Chem. 2015 May 14;58(9):4080-5. doi: 10.1021/acs.jmedchem.5b00166. Epub 2015 Apr 16. J Med Chem. 2015. PMID: 25839426
The future of peptide-based drugs.
Craik DJ, Fairlie DP, Liras S, Price D. Craik DJ, et al. Chem Biol Drug Des. 2013 Jan;81(1):136-47. doi: 10.1111/cbdd.12055. Chem Biol Drug Des. 2013. PMID: 23253135 Review.
Fmoc-based synthesis of disulfide-rich cyclic peptides.
Cheneval O, Schroeder CI, Durek T, Walsh P, Huang YH, Liras S, Price DA, Craik DJ. Cheneval O, et al. Among authors: price da. J Org Chem. 2014 Jun 20;79(12):5538-44. doi: 10.1021/jo500699m. Epub 2014 Jun 11. J Org Chem. 2014. PMID: 24918986
Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists.
Swedberg JE, Schroeder CI, Mitchell JM, Durek T, Fairlie DP, Edmonds DJ, Griffith DA, Ruggeri RB, Derksen DR, Loria PM, Liras S, Price DA, Craik DJ. Swedberg JE, et al. Among authors: price da. Eur J Med Chem. 2015 Oct 20;103:175-84. doi: 10.1016/j.ejmech.2015.08.046. Epub 2015 Aug 29. Eur J Med Chem. 2015. PMID: 26352676
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