Duncan JA - Search Results

1

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome.

Canna SW, de Jesus AA, Gouni S, Brooks SR, Marrero B, Liu Y, DiMattia MA, Zaal KJ, Sanchez GA, Kim H, Chapelle D, Plass N, Huang Y, Villarino AV, Biancotto A, Fleisher TA, Duncan JA, O'Shea JJ, Benseler S, Grom A, Deng Z, Laxer RM, Goldbach-Mansky R. Canna SW, et al. Among authors: duncan ja. Nat Genet. 2014 Oct;46(10):1140-6. doi: 10.1038/ng.3089. Epub 2014 Sep 14. Nat Genet. 2014. PMID: 25217959 Free PMC article.

2

NLRX1 is a regulator of mitochondrial antiviral immunity.

Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. Moore CB, et al. Among authors: duncan ja. Nature. 2008 Jan 31;451(7178):573-7. doi: 10.1038/nature06501. Epub 2008 Jan 16. Nature. 2008. PMID: 18200010

3

Cutting edge: NLRC5-dependent activation of the inflammasome.

Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Davis BK, et al. Among authors: duncan ja. J Immunol. 2011 Feb 1;186(3):1333-7. doi: 10.4049/jimmunol.1003111. Epub 2010 Dec 29. J Immunol. 2011. PMID: 21191067 Free PMC article.

4

The NLRC4 Inflammasome.

Duncan JA, Canna SW. Duncan JA, et al. Immunol Rev. 2018 Jan;281(1):115-123. doi: 10.1111/imr.12607. Immunol Rev. 2018. PMID: 29247997 Free PMC article. Review.

5

Novel aspects of the assembly and activation of inflammasomes with focus on the NLRC4 inflammasome.

Fusco WG, Duncan JA. Fusco WG, et al. Among authors: duncan ja. Int Immunol. 2018 Apr 25;30(5):183-193. doi: 10.1093/intimm/dxy009. Int Immunol. 2018. PMID: 29617808 Free PMC article. Review.

6

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling.

Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, Zimmermann AG, Ting JP. Duncan JA, et al. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8041-6. doi: 10.1073/pnas.0611496104. Epub 2007 May 2. Proc Natl Acad Sci U S A. 2007. PMID: 17483456 Free PMC article.

7

Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death.

McCall SH, Sahraei M, Young AB, Worley CS, Duncan JA, Ting JP, Marriott I. McCall SH, et al. Among authors: duncan ja. J Bone Miner Res. 2008 Jan;23(1):30-40. doi: 10.1359/jbmr.071002. J Bone Miner Res. 2008. PMID: 17907925 Free PMC article.

8

Rebuilding host-pathogen interaction from the ground up: in vitro reconstitution of the inflammasome.

Duncan JA, Ting JP. Duncan JA, et al. Cell Host Microbe. 2007 Mar 15;1(1):7-9. doi: 10.1016/j.chom.2007.02.007. Cell Host Microbe. 2007. PMID: 18005676 Free article.

9

Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, Ting JP. Willingham SB, et al. Among authors: duncan ja. Cell Host Microbe. 2007 Sep 13;2(3):147-59. doi: 10.1016/j.chom.2007.07.009. Cell Host Microbe. 2007. PMID: 18005730 Free PMC article.

10

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.

Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP. Duncan JA, et al. J Immunol. 2009 May 15;182(10):6460-9. doi: 10.4049/jimmunol.0802696. J Immunol. 2009. PMID: 19414800 Free PMC article.

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