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Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury.
Qu D, May R, Sureban SM, Weygant N, Chandrakesan P, Ali N, Li L, Barrett T, Houchen CW. Qu D, et al. Among authors: houchen cw. Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1;306(5):G404-11. doi: 10.1152/ajpgi.00088.2013. Epub 2013 Dec 24. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24368703 Free PMC article.
XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
Sureban SM, May R, Weygant N, Qu D, Chandrakesan P, Bannerman-Menson E, Ali N, Pantazis P, Westphalen CB, Wang TC, Houchen CW. Sureban SM, et al. Among authors: houchen cw. Cancer Lett. 2014 Aug 28;351(1):151-61. doi: 10.1016/j.canlet.2014.05.011. Epub 2014 May 28. Cancer Lett. 2014. PMID: 24880079
DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma.
Weygant N, Qu D, May R, Tierney RM, Berry WL, Zhao L, Agarwal S, Chandrakesan P, Chinthalapally HR, Murphy NT, Li JD, Sureban SM, Schlosser MJ, Tomasek JJ, Houchen CW. Weygant N, et al. Among authors: houchen cw. Oncotarget. 2015 Feb 10;6(4):2193-205. doi: 10.18632/oncotarget.3059. Oncotarget. 2015. PMID: 25605241 Free PMC article.
Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression.
Mohammed A, Janakiram NB, Madka V, Brewer M, Ritchie RL, Lightfoot S, Kumar G, Sadeghi M, Patlolla JM, Yamada HY, Cruz-Monserrate Z, May R, Houchen CW, Steele VE, Rao CV. Mohammed A, et al. Among authors: houchen cw. Oncotarget. 2015 Jun 20;6(17):15524-39. doi: 10.18632/oncotarget.3499. Oncotarget. 2015. PMID: 25906749 Free PMC article.
126 results