Wierenga RK - Search Results

1

Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.

Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z. Venkatesan R, et al. Among authors: wierenga rk. Nat Commun. 2014 Sep 9;5:4805. doi: 10.1038/ncomms5805. Nat Commun. 2014. PMID: 25203508 Free article.

2

Crystallization and preliminary X-ray diffraction studies of mitochondrial short-chain delta 3,delta 2-enoyl-CoA isomerase from rat liver.

Zeelen JP, Pauptit RA, Wierenga RK, Kunau WH, Hiltunen JK. Zeelen JP, et al. Among authors: wierenga rk. J Mol Biol. 1992 Mar 5;224(1):273-5. doi: 10.1016/0022-2836(92)90591-7. J Mol Biol. 1992. PMID: 1548706

3

Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 angstroms resolution: a spiral fold defines the CoA-binding pocket.

Engel CK, Mathieu M, Zeelen JP, Hiltunen JK, Wierenga RK. Engel CK, et al. Among authors: wierenga rk. EMBO J. 1996 Oct 1;15(19):5135-45. EMBO J. 1996. PMID: 8895557 Free PMC article.

4

The crystal structure of enoyl-CoA hydratase complexed with octanoyl-CoA reveals the structural adaptations required for binding of a long chain fatty acid-CoA molecule.

Engel CK, Kiema TR, Hiltunen JK, Wierenga RK. Engel CK, et al. Among authors: wierenga rk. J Mol Biol. 1998 Feb 6;275(5):847-59. doi: 10.1006/jmbi.1997.1491. J Mol Biol. 1998. PMID: 9480773

5

The crystal structure of dienoyl-CoA isomerase at 1.5 A resolution reveals the importance of aspartate and glutamate sidechains for catalysis.

Modis Y, Filppula SA, Novikov DK, Norledge B, Hiltunen JK, Wierenga RK. Modis Y, et al. Among authors: wierenga rk. Structure. 1998 Aug 15;6(8):957-70. doi: 10.1016/s0969-2126(98)00098-7. Structure. 1998. PMID: 9739087 Free article.

6

Mutagenic and enzymological studies of the hydratase and isomerase activities of 2-enoyl-CoA hydratase-1.

Kiema TR, Engel CK, Schmitz W, Filppula SA, Wierenga RK, Hiltunen JK. Kiema TR, et al. Among authors: wierenga rk. Biochemistry. 1999 Mar 9;38(10):2991-9. doi: 10.1021/bi981646v. Biochemistry. 1999. PMID: 10074351

7

Crystallization and X-ray diffraction analysis of peroxisomal Delta3-Delta2-enoyl-CoA isomerase from Saccharomyces cerevisiae.

Mursula AM, van Aalten DM, Modis Y, Hiltunen JK, Wierenga RK. Mursula AM, et al. Among authors: wierenga rk. Acta Crystallogr D Biol Crystallogr. 2000 Aug;56(Pt 8):1020-3. doi: 10.1107/s0907444900006533. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 10944342

8

The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase.

Mursula AM, van Aalten DM, Hiltunen JK, Wierenga RK. Mursula AM, et al. Among authors: wierenga rk. J Mol Biol. 2001 Jun 15;309(4):845-53. doi: 10.1006/jmbi.2001.4671. J Mol Biol. 2001. PMID: 11399063

9

Crystal structure of the liganded SCP-2-like domain of human peroxisomal multifunctional enzyme type 2 at 1.75 A resolution.

Haapalainen AM, van Aalten DM, Meriläinen G, Jalonen JE, Pirilä P, Wierenga RK, Hiltunen JK, Glumoff T. Haapalainen AM, et al. Among authors: wierenga rk. J Mol Biol. 2001 Nov 9;313(5):1127-38. doi: 10.1006/jmbi.2001.5084. J Mol Biol. 2001. PMID: 11700068

10

Crystallization and characterization of the dehydrogenase domain from rat peroxisomal multifunctional enzyme type 1.

Taskinen JP, Kiema TR, Koivuranta KT, Wierenga RK, Hiltunen JK. Taskinen JP, et al. Among authors: wierenga rk. Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):690-3. doi: 10.1107/s0907444902001890. Epub 2002 Mar 22. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 11914498

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