Heinen S - Search Results

1

A lymphatic defect causes ocular hypertension and glaucoma in mice.

Thomson BR, Heinen S, Jeansson M, Ghosh AK, Fatima A, Sung HK, Onay T, Chen H, Yamaguchi S, Economides AN, Flenniken A, Gale NW, Hong YK, Fawzi A, Liu X, Kume T, Quaggin SE. Thomson BR, et al. Among authors: heinen s. J Clin Invest. 2014 Oct;124(10):4320-4. doi: 10.1172/JCI77162. Epub 2014 Sep 9. J Clin Invest. 2014. PMID: 25202984 Free PMC article.

2

Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP.

Souma T, Thomson BR, Heinen S, Carota IA, Yamaguchi S, Onay T, Liu P, Ghosh AK, Li C, Eremina V, Hong YK, Economides AN, Vestweber D, Peters KG, Jin J, Quaggin SE. Souma T, et al. Among authors: heinen s. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1298-1303. doi: 10.1073/pnas.1714446115. Epub 2018 Jan 22. Proc Natl Acad Sci U S A. 2018. PMID: 29358379 Free PMC article.

3

Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.

Kenig-Kozlovsky Y, Scott RP, Onay T, Carota IA, Thomson BR, Gil HJ, Ramirez V, Yamaguchi S, Tanna CE, Heinen S, Wu C, Stan RV, Klein JD, Sands JM, Oliver G, Quaggin SE. Kenig-Kozlovsky Y, et al. Among authors: heinen s. J Am Soc Nephrol. 2018 Apr;29(4):1097-1107. doi: 10.1681/ASN.2017090962. Epub 2017 Dec 13. J Am Soc Nephrol. 2018. PMID: 29237738 Free PMC article.

4

Monitoring and modeling treatment of atypical hemolytic uremic syndrome.

Heinen S, Pluthero FG, van Eimeren VF, Quaggin SE, Licht C. Heinen S, et al. Mol Immunol. 2013 May;54(1):84-8. doi: 10.1016/j.molimm.2012.10.044. Epub 2012 Dec 3. Mol Immunol. 2013. PMID: 23220071

5

Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome.

Manuelian T, Hellwage J, Meri S, Caprioli J, Noris M, Heinen S, Jozsi M, Neumann HP, Remuzzi G, Zipfel PF. Manuelian T, et al. Among authors: heinen s. J Clin Invest. 2003 Apr;111(8):1181-90. doi: 10.1172/JCI16651. J Clin Invest. 2003. PMID: 12697737 Free PMC article.

6

Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer's disease.

Dubey S, Heinen S, Krantic S, McLaurin J, Branch DR, Hynynen K, Aubert I. Dubey S, et al. Among authors: heinen s. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32691-32700. doi: 10.1073/pnas.1908658117. Epub 2020 Dec 7. Proc Natl Acad Sci U S A. 2020. PMID: 33288687 Free PMC article.

7

Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H deficiency owing to a novel mutation in the complement cofactor protein domain 15.

Licht C, Weyersberg A, Heinen S, Stapenhorst L, Devenge J, Beck B, Waldherr R, Kirschfink M, Zipfel PF, Hoppe B. Licht C, et al. Among authors: heinen s. Am J Kidney Dis. 2005 Feb;45(2):415-21. doi: 10.1053/j.ajkd.2004.10.018. Am J Kidney Dis. 2005. PMID: 15685522

8

Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency.

Józsi M, Licht C, Strobel S, Zipfel SL, Richter H, Heinen S, Zipfel PF, Skerka C. Józsi M, et al. Among authors: heinen s. Blood. 2008 Feb 1;111(3):1512-4. doi: 10.1182/blood-2007-09-109876. Epub 2007 Nov 15. Blood. 2008. PMID: 18006700 Free article.

9

Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions.

Józsi M, Heinen S, Hartmann A, Ostrowicz CW, Hälbich S, Richter H, Kunert A, Licht C, Saunders RE, Perkins SJ, Zipfel PF, Skerka C. Józsi M, et al. Among authors: heinen s. J Am Soc Nephrol. 2006 Jan;17(1):170-7. doi: 10.1681/ASN.2005080868. Epub 2005 Dec 7. J Am Soc Nephrol. 2006. PMID: 16338962

10

Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.

Zipfel PF, Edey M, Heinen S, Józsi M, Richter H, Misselwitz J, Hoppe B, Routledge D, Strain L, Hughes AE, Goodship JA, Licht C, Goodship TH, Skerka C. Zipfel PF, et al. Among authors: heinen s. PLoS Genet. 2007 Mar 16;3(3):e41. doi: 10.1371/journal.pgen.0030041. Epub 2007 Feb 1. PLoS Genet. 2007. PMID: 17367211 Free PMC article.

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