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Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity.
Izaguirre-Carbonell J, Kawakubo H, Murata H, Tanabe A, Takeuchi T, Kusayanagi T, Tsukuda S, Hirakawa T, Iwabata K, Kanai Y, Ohta K, Miura M, Sakaguchi K, Matsunaga S, Sahara H, Kamisuki S, Sugawara F. Izaguirre-Carbonell J, et al. Among authors: takeuchi t. Sci Rep. 2015 Oct 12;5:15136. doi: 10.1038/srep15136. Sci Rep. 2015. PMID: 26456697 Free PMC article.
Pyrenocine A induces monopolar spindle formation and suppresses proliferation of cancer cells.
Myobatake Y, Kamisuki S, Tsukuda S, Higashi T, Chinen T, Takemoto K, Hachisuka M, Suzuki Y, Takei M, Tsurukawa Y, Maekawa H, Takeuchi T, Matsunaga TM, Sahara H, Usui T, Matsunaga S, Sugawara F. Myobatake Y, et al. Among authors: takeuchi t. Bioorg Med Chem. 2019 Dec 1;27(23):115149. doi: 10.1016/j.bmc.2019.115149. Epub 2019 Oct 15. Bioorg Med Chem. 2019. PMID: 31679979
The antitumor agent doxorubicin binds to Fanconi anemia group F protein.
Kusayanagi T, Tsukuda S, Shimura S, Manita D, Iwakiri K, Kamisuki S, Takakusagi Y, Takeuchi T, Kuramochi K, Nakazaki A, Sakaguchi K, Kobayashi S, Sugawara F. Kusayanagi T, et al. Among authors: takeuchi t. Bioorg Med Chem. 2012 Nov 1;20(21):6248-55. doi: 10.1016/j.bmc.2012.09.015. Epub 2012 Sep 16. Bioorg Med Chem. 2012. PMID: 23026082
Exploration of the binding proteins of perfluorooctane sulfonate by a T7 phage display screen.
Miyano Y, Tsukuda S, Sakimoto I, Takeuchi R, Shimura S, Takahashi N, Kusayanagi T, Takakusagi Y, Okado M, Matsumoto Y, Takakusagi K, Takeuchi T, Kamisuki S, Nakazaki A, Ohta K, Miura M, Kuramochi K, Mizushina Y, Kobayashi S, Sugawara F, Sakaguchi K. Miyano Y, et al. Among authors: takeuchi t, takeuchi r. Bioorg Med Chem. 2012 Jul 1;20(13):3985-90. doi: 10.1016/j.bmc.2012.05.016. Epub 2012 May 15. Bioorg Med Chem. 2012. PMID: 22658539
Synthesis of nucleotide analogues, EFdA, EdA and EdAP, and the effect of EdAP on hepatitis B virus replication.
Kamata M, Takeuchi T, Hayashi E, Nishioka K, Oshima M, Iwamoto M, Nishiuchi K, Kamo S, Tomoshige S, Watashi K, Kamisuki S, Ohrui H, Sugawara F, Kuramochi K. Kamata M, et al. Among authors: takeuchi t. Biosci Biotechnol Biochem. 2020 Feb;84(2):217-227. doi: 10.1080/09168451.2019.1673696. Epub 2019 Oct 7. Biosci Biotechnol Biochem. 2020. PMID: 31589093
5,724 results