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De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group; O'Connor TD. Kessler MD, et al. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964835 Free PMC article.
Fused Lasso Additive Model.
Petersen A, Witten D, Simon N. Petersen A, et al. Among authors: simon n. J Comput Graph Stat. 2016;25(4):1005-1025. doi: 10.1080/10618600.2015.1073155. Epub 2016 Nov 10. J Comput Graph Stat. 2016. PMID: 28239246 Free PMC article.
Epigenetic memory via concordant DNA methylation is inversely correlated to developmental potential of mammalian cells.
Choi M, Genereux DP, Goodson J, Al-Azzawi H, Allain SQ, Simon N, Palasek S, Ware CB, Cavanaugh C, Miller DG, Johnson WC, Sinclair KD, Stöger R, Laird CD. Choi M, et al. Among authors: simon n. PLoS Genet. 2017 Nov 6;13(11):e1007060. doi: 10.1371/journal.pgen.1007060. eCollection 2017 Nov. PLoS Genet. 2017. PMID: 29107996 Free PMC article.
1,537 results