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Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.
Wu X, Zhang W, Font-Burgada J, Palmer T, Hamil AS, Biswas SK, Poidinger M, Borcherding N, Xie Q, Ellies LG, Lytle NK, Wu LW, Fox RG, Yang J, Dowdy SF, Reya T, Karin M. Wu X, et al. Among authors: ellies lg. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13870-5. doi: 10.1073/pnas.1414358111. Epub 2014 Sep 4. Proc Natl Acad Sci U S A. 2014. PMID: 25189770 Free PMC article.
PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes.
Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J. Garmy-Susini B, et al. Among authors: ellies lg. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9042-7. doi: 10.1073/pnas.1219603110. Epub 2013 May 13. Proc Natl Acad Sci U S A. 2013. PMID: 23671068 Free PMC article.
Obesity-associated NLRC4 inflammasome activation drives breast cancer progression.
Kolb R, Phan L, Borcherding N, Liu Y, Yuan F, Janowski AM, Xie Q, Markan KR, Li W, Potthoff MJ, Fuentes-Mattei E, Ellies LG, Knudson CM, Lee MH, Yeung SJ, Cassel SL, Sutterwala FS, Zhang W. Kolb R, et al. Among authors: ellies lg. Nat Commun. 2016 Oct 6;7:13007. doi: 10.1038/ncomms13007. Nat Commun. 2016. PMID: 27708283 Free PMC article.
Elevated BCAA Suppresses the Development and Metastasis of Breast Cancer.
Chi R, Yao C, Chen S, Liu Y, He Y, Zhang J, Ellies LG, Wu X, Zhao Q, Zhou C, Wang Y, Sun H. Chi R, et al. Among authors: ellies lg. Front Oncol. 2022 Jun 16;12:887257. doi: 10.3389/fonc.2022.887257. eCollection 2022. Front Oncol. 2022. PMID: 35785192 Free PMC article.
Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.
Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. Garmy-Susini B, et al. Among authors: ellies lg. Cancer Res. 2010 Apr 15;70(8):3042-51. doi: 10.1158/0008-5472.CAN-09-3761. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388801 Free PMC article.
Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.
Schmid MC, Avraamides CJ, Dippold HC, Franco I, Foubert P, Ellies LG, Acevedo LM, Manglicmot JR, Song X, Wrasidlo W, Blair SL, Ginsberg MH, Cheresh DA, Hirsch E, Field SJ, Varner JA. Schmid MC, et al. Among authors: ellies lg. Cancer Cell. 2011 Jun 14;19(6):715-27. doi: 10.1016/j.ccr.2011.04.016. Cancer Cell. 2011. PMID: 21665146 Free PMC article.
85 results