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Mechanisms underlying the hypotensive and vasodilator effects of Ru(terpy)(bdq)NO](3+), a nitric oxide donor, differ between normotensive and spontaneously hypertensive rats.
Potje SR, Munhoz FC, Perassa LA, Graton ME, Pereira AA, Nakamune AC, da Silva RS, Bendhack LM, Sumida DH, Antoniali C. Potje SR, et al. Among authors: munhoz fc. Eur J Pharmacol. 2014 Oct 15;741:222-9. doi: 10.1016/j.ejphar.2014.08.008. Epub 2014 Aug 29. Eur J Pharmacol. 2014. PMID: 25179868
The hypotensive effect of the ruthenium complex [Ru(terpy)(bdq)NO]³⁺ is higher in male than in female spontaneously hypertensive rats (SHR).
Potje SR, Hildebrand MC, Munhoz FC, Troiano JA, Pereira AA, Nakamune AC, da Silva RS, Bendhack LM, Antoniali C. Potje SR, et al. Among authors: munhoz fc. Naunyn Schmiedebergs Arch Pharmacol. 2014 Nov;387(11):1045-51. doi: 10.1007/s00210-014-1020-2. Epub 2014 Jul 29. Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID: 25066265