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Cardiac overexpression of constitutively active Galpha q causes angiotensin II type1 receptor activation, leading to progressive heart failure and ventricular arrhythmias in transgenic mice.
Matsushita N, Kashihara T, Shimojo H, Suzuki S, Nakada T, Takeishi Y, Mende U, Taira E, Yamada M, Sanbe A, Hirose M. Matsushita N, et al. Among authors: takeishi y. PLoS One. 2014 Aug 29;9(8):e106354. doi: 10.1371/journal.pone.0106354. eCollection 2014. PLoS One. 2014. PMID: 25171374 Free PMC article.
Diacylglycerol kinase-epsilon restores cardiac dysfunction under chronic pressure overload: a new specific regulator of Galpha(q) signaling cascade.
Niizeki T, Takeishi Y, Kitahara T, Arimoto T, Ishino M, Bilim O, Suzuki S, Sasaki T, Nakajima O, Walsh RA, Goto K, Kubota I. Niizeki T, et al. Among authors: takeishi y. Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H245-55. doi: 10.1152/ajpheart.00066.2008. Epub 2008 May 16. Am J Physiol Heart Circ Physiol. 2008. PMID: 18487437 Free article.
641 results