Philp A - Search Results

1

High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression.

White AT, Philp A, Fridolfsson HN, Schilling JM, Murphy AN, Hamilton DL, McCurdy CE, Patel HH, Schenk S. White AT, et al. Among authors: philp a. Am J Physiol Endocrinol Metab. 2014 Nov 1;307(9):E764-72. doi: 10.1152/ajpendo.00001.2014. Epub 2014 Aug 26. Am J Physiol Endocrinol Metab. 2014. PMID: 25159328 Free PMC article.

2

Pyruvate suppresses PGC1alpha expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes.

Philp A, Perez-Schindler J, Green C, Hamilton DL, Baar K. Philp A, et al. Am J Physiol Cell Physiol. 2010 Aug;299(2):C240-50. doi: 10.1152/ajpcell.00438.2009. Epub 2010 Apr 21. Am J Physiol Cell Physiol. 2010. PMID: 20410436 Free PMC article.

3

The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesis.

Deldicque L, Cani PD, Philp A, Raymackers JM, Meakin PJ, Ashford ML, Delzenne NM, Francaux M, Baar K. Deldicque L, et al. Among authors: philp a. Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E695-705. doi: 10.1152/ajpendo.00038.2010. Epub 2010 May 25. Am J Physiol Endocrinol Metab. 2010. PMID: 20501874 Free article.

4

Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation.

Hamilton DL, Philp A, MacKenzie MG, Baar K. Hamilton DL, et al. Among authors: philp a. BMC Cell Biol. 2010 May 27;11:37. doi: 10.1186/1471-2121-11-37. BMC Cell Biol. 2010. PMID: 20507574 Free PMC article.

5

Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. Irrelevant growth factor-I.

Baar K, Hamilton DL, Philp A. Baar K, et al. Among authors: philp a. J Appl Physiol (1985). 2010 Jun;108(6):1827. doi: 10.1152/japplphysiol.00312.2010. J Appl Physiol (1985). 2010. PMID: 20527696 Free article. No abstract available.

6

A limited role for PI(3,4,5)P3 regulation in controlling skeletal muscle mass in response to resistance exercise.

Hamilton DL, Philp A, MacKenzie MG, Baar K. Hamilton DL, et al. Among authors: philp a. PLoS One. 2010 Jul 16;5(7):e11624. doi: 10.1371/journal.pone.0011624. PLoS One. 2010. PMID: 20661274 Free PMC article.

7

Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1.

Philp A, Hamilton DL, Baar K. Philp A, et al. J Appl Physiol (1985). 2011 Feb;110(2):561-8. doi: 10.1152/japplphysiol.00941.2010. Epub 2010 Nov 11. J Appl Physiol (1985). 2011. PMID: 21071597 Free article.

8

Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise.

Philp A, Chen A, Lan D, Meyer GA, Murphy AN, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K, Schenk S. Philp A, et al. J Biol Chem. 2011 Sep 2;286(35):30561-30570. doi: 10.1074/jbc.M111.261685. Epub 2011 Jul 11. J Biol Chem. 2011. PMID: 21757760 Free PMC article.

9

The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes.

Philp A, Belew MY, Evans A, Pham D, Sivia I, Chen A, Schenk S, Baar K. Philp A, et al. Am J Physiol Regul Integr Comp Physiol. 2011 Oct;301(4):R864-72. doi: 10.1152/ajpregu.00232.2011. Epub 2011 Jul 27. Am J Physiol Regul Integr Comp Physiol. 2011. PMID: 21795630 Free PMC article.

10

Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction.

Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, Bandyopadhyay GK, Osborn O, Baar K, Olefsky JM. Schenk S, et al. Among authors: philp a. J Clin Invest. 2011 Nov;121(11):4281-8. doi: 10.1172/JCI58554. Epub 2011 Oct 10. J Clin Invest. 2011. PMID: 21985785 Free PMC article.

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