Wang JL - Search Results

1

Label-free, live optical imaging of reprogrammed bipolar disorder patient-derived cells reveals a functional correlate of lithium responsiveness.

Wang JL, Shamah SM, Sun AX, Waldman ID, Haggarty SJ, Perlis RH. Wang JL, et al. Transl Psychiatry. 2014 Aug 26;4(8):e428. doi: 10.1038/tp.2014.72. Transl Psychiatry. 2014. PMID: 25158003 Free PMC article. Review.

2

Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder.

Bavamian S, Mellios N, Lalonde J, Fass DM, Wang J, Sheridan SD, Madison JM, Zhou F, Rueckert EH, Barker D, Perlis RH, Sur M, Haggarty SJ. Bavamian S, et al. Mol Psychiatry. 2015 May;20(5):573-84. doi: 10.1038/mp.2014.176. Epub 2015 Jan 27. Mol Psychiatry. 2015. PMID: 25623948 Free PMC article.

3

Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning.

Sellgren CM, Gracias J, Watmuff B, Biag JD, Thanos JM, Whittredge PB, Fu T, Worringer K, Brown HE, Wang J, Kaykas A, Karmacharya R, Goold CP, Sheridan SD, Perlis RH. Sellgren CM, et al. Nat Neurosci. 2019 Mar;22(3):374-385. doi: 10.1038/s41593-018-0334-7. Epub 2019 Feb 4. Nat Neurosci. 2019. PMID: 30718903 Free PMC article.

4

Deep Learning Benchmarks on L1000 Gene Expression Data.

McDermott MBA, Wang J, Zhao WN, Sheridan SD, Szolovits P, Kohane I, Haggarty SJ, Perlis RH. McDermott MBA, et al. IEEE/ACM Trans Comput Biol Bioinform. 2020 Nov-Dec;17(6):1846-1857. doi: 10.1109/TCBB.2019.2910061. Epub 2020 Dec 8. IEEE/ACM Trans Comput Biol Bioinform. 2020. PMID: 30990190 Free PMC article.

5

Activation of WNT and CREB signaling pathways in human neuronal cells in response to the Omega-3 fatty acid docosahexaenoic acid (DHA).

Zhao WN, Hylton NK, Wang J, Chindavong PS, Alural B, Kurtser I, Subramanian A, Mazitschek R, Perlis RH, Haggarty SJ. Zhao WN, et al. Mol Cell Neurosci. 2019 Sep;99:103386. doi: 10.1016/j.mcn.2019.06.006. Epub 2019 Jun 14. Mol Cell Neurosci. 2019. PMID: 31202891 Free PMC article.

6

Aberrant mitochondrial function in patient-derived neural cells from CDKL5 deficiency disorder and Rett syndrome.

Jagtap S, Thanos JM, Fu T, Wang J, Lalonde J, Dial TO, Feiglin A, Chen J, Kohane I, Lee JT, Sheridan SD, Perlis RH. Jagtap S, et al. Hum Mol Genet. 2019 Nov 1;28(21):3625-3636. doi: 10.1093/hmg/ddz208. Hum Mol Genet. 2019. PMID: 31518399 Free PMC article.

7

N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells.

Yu JZ, Wang J, Sheridan SD, Perlis RH, Rasenick MM. Yu JZ, et al. Mol Psychiatry. 2021 Sep;26(9):4605-4615. doi: 10.1038/s41380-020-0786-5. Epub 2020 Jun 5. Mol Psychiatry. 2021. PMID: 32504049 Free PMC article.

8

Tissue- and cell-type-specific molecular and functional signatures of 16p11.2 reciprocal genomic disorder across mouse brain and human neuronal models.

Tai DJC, Razaz P, Erdin S, Gao D, Wang J, Nuttle X, de Esch CE, Collins RL, Currall BB, O'Keefe K, Burt ND, Yadav R, Wang L, Mohajeri K, Aneichyk T, Ragavendran A, Stortchevoi A, Morini E, Ma W, Lucente D, Hastie A, Kelleher RJ, Perlis RH, Talkowski ME, Gusella JF. Tai DJC, et al. Am J Hum Genet. 2022 Oct 6;109(10):1789-1813. doi: 10.1016/j.ajhg.2022.08.012. Epub 2022 Sep 23. Am J Hum Genet. 2022. PMID: 36152629 Free PMC article.

9

Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca²⁺ entry and accelerated differentiation.

Hewitt T, Alural B, Tilak M, Wang J, Becke N, Chartley E, Perreault M, Haggarty SJ, Sheridan SD, Perlis RH, Jones N, Mellios N, Lalonde J. Hewitt T, et al. Mol Psychiatry. 2023 Dec;28(12):5237-5250. doi: 10.1038/s41380-023-02152-6. Epub 2023 Jul 4. Mol Psychiatry. 2023. PMID: 37402854 Free PMC article.

10

Loss of Function in the Neurodevelopmental Disease and Schizophrenia-Associated Gene CYFIP1 in Human Microglia-like Cells Supports a Functional Role in Synaptic Engulfment.

Sheridan SD, Horng JE, Yeh H, McCrea L, Wang J, Fu T, Perlis RH. Sheridan SD, et al. Biol Psychiatry. 2024 Apr 1;95(7):676-686. doi: 10.1016/j.biopsych.2023.07.022. Epub 2023 Aug 11. Biol Psychiatry. 2024. PMID: 37573007

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