Brereton MF - Search Results

1

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.

Brereton MF, Iberl M, Shimomura K, Zhang Q, Adriaenssens AE, Proks P, Spiliotis II, Dace W, Mattis KK, Ramracheya R, Gribble FM, Reimann F, Clark A, Rorsman P, Ashcroft FM. Brereton MF, et al. Nat Commun. 2014 Aug 22;5:4639. doi: 10.1038/ncomms5639. Nat Commun. 2014. PMID: 25145789 Free PMC article.

2

Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.

Zhang Q, Ramracheya R, Lahmann C, Tarasov A, Bengtsson M, Braha O, Braun M, Brereton M, Collins S, Galvanovskis J, Gonzalez A, Groschner LN, Rorsman NJ, Salehi A, Travers ME, Walker JN, Gloyn AL, Gribble F, Johnson PR, Reimann F, Ashcroft FM, Rorsman P. Zhang Q, et al. Cell Metab. 2013 Dec 3;18(6):871-82. doi: 10.1016/j.cmet.2013.10.014. Cell Metab. 2013. PMID: 24315372 Free PMC article.

3

A mouse model of human hyperinsulinism produced by the E1506K mutation in the sulphonylurea receptor SUR1.

Shimomura K, Tusa M, Iberl M, Brereton MF, Kaizik S, Proks P, Lahmann C, Yaluri N, Modi S, Huopio H, Ustinov J, Otonkoski T, Laakso M, Ashcroft FM. Shimomura K, et al. Among authors: brereton mf. Diabetes. 2013 Nov;62(11):3797-806. doi: 10.2337/db12-1611. Epub 2013 Jul 31. Diabetes. 2013. PMID: 23903354 Free PMC article.

4

Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?

Brereton MF, Vergari E, Zhang Q, Clark A. Brereton MF, et al. J Histochem Cytochem. 2015 Aug;63(8):575-91. doi: 10.1369/0022155415583535. J Histochem Cytochem. 2015. PMID: 26216135 Free PMC article. Review.

5

Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells.

Brereton MF, Rohm M, Shimomura K, Holland C, Tornovsky-Babeay S, Dadon D, Iberl M, Chibalina MV, Lee S, Glaser B, Dor Y, Rorsman P, Clark A, Ashcroft FM. Brereton MF, et al. Nat Commun. 2016 Nov 24;7:13496. doi: 10.1038/ncomms13496. Nat Commun. 2016. PMID: 27882918 Free PMC article.

6

Is Type 2 Diabetes a Glycogen Storage Disease of Pancreatic β Cells?

Ashcroft FM, Rohm M, Clark A, Brereton MF. Ashcroft FM, et al. Among authors: brereton mf. Cell Metab. 2017 Jul 5;26(1):17-23. doi: 10.1016/j.cmet.2017.05.014. Cell Metab. 2017. PMID: 28683284 Free PMC article. Review.

7

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.

Haythorne E, Rohm M, van de Bunt M, Brereton MF, Tarasov AI, Blacker TS, Sachse G, Silva Dos Santos M, Terron Exposito R, Davis S, Baba O, Fischer R, Duchen MR, Rorsman P, MacRae JI, Ashcroft FM. Haythorne E, et al. Among authors: brereton mf. Nat Commun. 2019 Jun 6;10(1):2474. doi: 10.1038/s41467-019-10189-x. Nat Commun. 2019. PMID: 31171772 Free PMC article.

8

β-Cell dysfunction in diabetes: a crisis of identity?

Brereton MF, Rohm M, Ashcroft FM. Brereton MF, et al. Diabetes Obes Metab. 2016 Sep;18 Suppl 1(Suppl 1):102-9. doi: 10.1111/dom.12732. Diabetes Obes Metab. 2016. PMID: 27615138 Free PMC article. Review.

9

Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production.

Knudsen JG, Hamilton A, Ramracheya R, Tarasov AI, Brereton M, Haythorne E, Chibalina MV, Spégel P, Mulder H, Zhang Q, Ashcroft FM, Adam J, Rorsman P. Knudsen JG, et al. Cell Metab. 2019 Feb 5;29(2):430-442.e4. doi: 10.1016/j.cmet.2018.10.003. Epub 2018 Nov 8. Cell Metab. 2019. PMID: 30415925 Free PMC article.

10

Mouse Models of β-cell K_ATP Channel Dysfunction.

Brereton MF, Ashcroft FM. Brereton MF, et al. Drug Discov Today Dis Models. 2013 Summer;10(2):e101-e109. doi: 10.1016/j.ddmod.2013.02.001. Drug Discov Today Dis Models. 2013. PMID: 29643927 Free PMC article.

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