Lesic B - Search Results

1

Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity.

Starkey M, Lepine F, Maura D, Bandyopadhaya A, Lesic B, He J, Kitao T, Righi V, Milot S, Tzika A, Rahme L. Starkey M, et al. Among authors: lesic b. PLoS Pathog. 2014 Aug 21;10(8):e1004321. doi: 10.1371/journal.ppat.1004321. eCollection 2014 Aug. PLoS Pathog. 2014. PMID: 25144274 Free PMC article.

2

Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis.

Lesic B, Starkey M, He J, Hazan R, Rahme LG. Lesic B, et al. Microbiology (Reading). 2009 Sep;155(Pt 9):2845-2855. doi: 10.1099/mic.0.029082-0. Epub 2009 Jun 4. Microbiology (Reading). 2009. PMID: 19497948 Free PMC article.

3

Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance.

Maura D, Drees SL, Bandyopadhaya A, Kitao T, Negri M, Starkey M, Lesic B, Milot S, Déziel E, Zahler R, Pucci M, Felici A, Fetzner S, Lépine F, Rahme LG. Maura D, et al. Among authors: lesic b. ACS Chem Biol. 2017 May 19;12(5):1435-1443. doi: 10.1021/acschembio.6b01139. Epub 2017 Apr 12. ACS Chem Biol. 2017. PMID: 28379691

4

A natural system of chromosome transfer in Yersinia pseudotuberculosis.

Lesic B, Zouine M, Ducos-Galand M, Huon C, Rosso ML, Prévost MC, Mazel D, Carniel E. Lesic B, et al. PLoS Genet. 2012;8(3):e1002529. doi: 10.1371/journal.pgen.1002529. Epub 2012 Mar 8. PLoS Genet. 2012. PMID: 22412380 Free PMC article.

5

A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes.

Kesarwani M, Hazan R, He J, Que YA, Apidianakis Y, Lesic B, Xiao G, Dekimpe V, Milot S, Deziel E, Lépine F, Rahme LG. Kesarwani M, et al. Among authors: lesic b. PLoS Pathog. 2011 Aug;7(8):e1002192. doi: 10.1371/journal.ppat.1002192. Epub 2011 Aug 4. PLoS Pathog. 2011. PMID: 21829370 Free PMC article.

6

Homeostatic interplay between bacterial cell-cell signaling and iron in virulence.

Hazan R, He J, Xiao G, Dekimpe V, Apidianakis Y, Lesic B, Astrakas C, Déziel E, Lépine F, Rahme LG. Hazan R, et al. Among authors: lesic b. PLoS Pathog. 2010 Mar 12;6(3):e1000810. doi: 10.1371/journal.ppat.1000810. PLoS Pathog. 2010. PMID: 20300606 Free PMC article.

7

Use of the lambda Red recombinase system to rapidly generate mutants in Pseudomonas aeruginosa.

Lesic B, Rahme LG. Lesic B, et al. BMC Mol Biol. 2008 Feb 4;9:20. doi: 10.1186/1471-2199-9-20. BMC Mol Biol. 2008. PMID: 18248677 Free PMC article.

8

Inhibitors of pathogen intercellular signals as selective anti-infective compounds.

Lesic B, Lépine F, Déziel E, Zhang J, Zhang Q, Padfield K, Castonguay MH, Milot S, Stachel S, Tzika AA, Tompkins RG, Rahme LG. Lesic B, et al. PLoS Pathog. 2007 Sep 14;3(9):1229-39. doi: 10.1371/journal.ppat.0030126. PLoS Pathog. 2007. PMID: 17941706 Free PMC article.

9

PqsA is required for the biosynthesis of 2,4-dihydroxyquinoline (DHQ), a newly identified metabolite produced by Pseudomonas aeruginosa and Burkholderia thailandensis.

Lépine F, Dekimpe V, Lesic B, Milot S, Lesimple A, Mamer OA, Rahme LG, Déziel E. Lépine F, et al. Among authors: lesic b. Biol Chem. 2007 Aug;388(8):839-45. doi: 10.1515/BC.2007.100. Biol Chem. 2007. PMID: 17655503 Free PMC article.

10

MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class regulatory protein, has dual ligands.

Xiao G, Déziel E, He J, Lépine F, Lesic B, Castonguay MH, Milot S, Tampakaki AP, Stachel SE, Rahme LG. Xiao G, et al. Among authors: lesic b. Mol Microbiol. 2006 Dec;62(6):1689-99. doi: 10.1111/j.1365-2958.2006.05462.x. Mol Microbiol. 2006. PMID: 17083468 Free article.

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