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Endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation.
Guiliano DB, Fussell H, Lenart I, Tsao E, Nesbeth D, Fletcher AJ, Campbell EC, Yousaf N, Williams S, Santos S, Cameron A, Towers GJ, Kellam P, Hebert DN, Gould KG, Powis SJ, Antoniou AN. Guiliano DB, et al. Among authors: fletcher aj. Arthritis Rheumatol. 2014 Nov;66(11):2976-88. doi: 10.1002/art.38809. Arthritis Rheumatol. 2014. PMID: 25132672 Free PMC article.
HIV-1 evades innate immune recognition through specific cofactor recruitment.
Rasaiyaah J, Tan CP, Fletcher AJ, Price AJ, Blondeau C, Hilditch L, Jacques DA, Selwood DL, James LC, Noursadeghi M, Towers GJ. Rasaiyaah J, et al. Among authors: fletcher aj. Nature. 2013 Nov 21;503(7476):402-405. doi: 10.1038/nature12769. Epub 2013 Nov 6. Nature. 2013. PMID: 24196705 Free PMC article.
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.
Schaller T, Ocwieja KE, Rasaiyaah J, Price AJ, Brady TL, Roth SL, Hué S, Fletcher AJ, Lee K, KewalRamani VN, Noursadeghi M, Jenner RG, James LC, Bushman FD, Towers GJ. Schaller T, et al. Among authors: fletcher aj. PLoS Pathog. 2011 Dec;7(12):e1002439. doi: 10.1371/journal.ppat.1002439. Epub 2011 Dec 8. PLoS Pathog. 2011. PMID: 22174692 Free PMC article.
CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.
Price AJ, Fletcher AJ, Schaller T, Elliott T, Lee K, KewalRamani VN, Chin JW, Towers GJ, James LC. Price AJ, et al. Among authors: fletcher aj. PLoS Pathog. 2012;8(8):e1002896. doi: 10.1371/journal.ppat.1002896. Epub 2012 Aug 30. PLoS Pathog. 2012. PMID: 22956906 Free PMC article.
135 results