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Design, synthesis, and structure-activity relationship studies of a series of [4-(4-carboxamidobutyl)]-1-arylpiperazines: insights into structural features contributing to dopamine D3 versus D2 receptor subtype selectivity.
Ananthan S, Saini SK, Zhou G, Hobrath JV, Padmalayam I, Zhai L, Bostwick JR, Antonio T, Reith ME, McDowell S, Cho E, McAleer L, Taylor M, Luedtke RR. Ananthan S, et al. Among authors: zhai l. J Med Chem. 2014 Aug 28;57(16):7042-60. doi: 10.1021/jm500801r. Epub 2014 Aug 15. J Med Chem. 2014. PMID: 25126833 Free PMC article.
KIFC1 is a novel potential therapeutic target for breast cancer.
Li Y, Lu W, Chen D, Boohaker RJ, Zhai L, Padmalayam I, Wennerberg K, Xu B, Zhang W. Li Y, et al. Among authors: zhai l. Cancer Biol Ther. 2015;16(9):1316-22. doi: 10.1080/15384047.2015.1070980. Epub 2015 Jul 15. Cancer Biol Ther. 2015. PMID: 26177331 Free PMC article.
Discovery of a novel inhibitor of kinesin-like protein KIFC1.
Zhang W, Zhai L, Wang Y, Boohaker RJ, Lu W, Gupta VV, Padmalayam I, Bostwick RJ, White EL, Ross LJ, Maddry J, Ananthan S, Augelli-Szafran CE, Suto MJ, Xu B, Li R, Li Y. Zhang W, et al. Among authors: zhai l. Biochem J. 2016 Apr 15;473(8):1027-35. doi: 10.1042/BJ20150992. Epub 2016 Feb 4. Biochem J. 2016. PMID: 26846349 Free PMC article.
Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals.
Yatchang MF, Mathew B, Srivastava RK, Khan J, Muzaffar S, Zhang S, Wu M, Zhai L, Ruiz P, Agarwal A, Bostwick JR, Suto MJ, Athar M, Augelli-Szafran CE. Yatchang MF, et al. Among authors: zhai l. Bioorg Med Chem Lett. 2022 May 15;64:128696. doi: 10.1016/j.bmcl.2022.128696. Epub 2022 Mar 19. Bioorg Med Chem Lett. 2022. PMID: 35318165 Free PMC article.
A high-throughput response to the SARS-CoV-2 pandemic.
Rasmussen L, Sanders S, Sosa M, McKellip S, Nebane NM, Martinez-Gzegozewska Y, Reece A, Ruiz P, Manuvakhova A, Zhai L, Warren B, Curry A, Zeng Q, Bostwick JR, Vinson PN. Rasmussen L, et al. Among authors: zhai l. SLAS Discov. 2024 Jul;29(5):100160. doi: 10.1016/j.slasd.2024.100160. Epub 2024 May 16. SLAS Discov. 2024. PMID: 38761981 Free article.
Identification of Cytoprotective Small-Molecule Inducers of Heme-Oxygenase-1.
Ghajar-Rahimi G, Traylor AM, Mathew B, Bostwick JR, Nebane NM, Zmijewska AA, Esman SK, Thukral S, Zhai L, Sambandam V, Cowell RM, Suto MJ, George JF, Augelli-Szafran CE, Agarwal A. Ghajar-Rahimi G, et al. Among authors: zhai l. Antioxidants (Basel). 2022 Sep 23;11(10):1888. doi: 10.3390/antiox11101888. Antioxidants (Basel). 2022. PMID: 36290611 Free PMC article.
Role of Bmi1 in H2A ubiquitylation and Hox gene silencing.
Wei J, Zhai L, Xu J, Wang H. Wei J, et al. Among authors: zhai l. J Biol Chem. 2006 Aug 11;281(32):22537-44. doi: 10.1074/jbc.M600826200. Epub 2006 Jun 4. J Biol Chem. 2006. PMID: 16751658 Free article.
1,648 results