Wacher VJ - Search Results

1

Efficacy and safety of oral methazolamide in patients with type 2 diabetes: a 24-week, placebo-controlled, double-blind study.

Simpson RW, Nicholson GC, Proietto J, Sarah A, Sanders KM, Phillips G, Chambers J, MacGinley R, Orford N, Walder K, Krippner G, Skoff K, Wacher VJ. Simpson RW, et al. Among authors: wacher vj. Diabetes Care. 2014 Nov;37(11):3121-3. doi: 10.2337/dc14-1038. Epub 2014 Aug 14. Diabetes Care. 2014. PMID: 25125506 Clinical Trial.

2

Use of ribaxamase (SYN-004), a β-lactamase, to prevent Clostridium difficile infection in β-lactam-treated patients: a double-blind, phase 2b, randomised placebo-controlled trial.

Kokai-Kun JF, Roberts T, Coughlin O, Le C, Whalen H, Stevenson R, Wacher VJ, Sliman J. Kokai-Kun JF, et al. Among authors: wacher vj. Lancet Infect Dis. 2019 May;19(5):487-496. doi: 10.1016/S1473-3099(18)30731-X. Epub 2019 Mar 15. Lancet Infect Dis. 2019. PMID: 30885591 Clinical Trial.

3

Development of a Modified-Release Formulation of Lovastatin Targeted to Intestinal Methanogens Implicated in Irritable Bowel Syndrome With Constipation.

Hubert S, Chadwick A, Wacher V, Coughlin O, Kokai-Kun J, Bristol A. Hubert S, et al. J Pharm Sci. 2018 Feb;107(2):662-671. doi: 10.1016/j.xphs.2017.09.028. Epub 2017 Oct 6. J Pharm Sci. 2018. PMID: 28989013 Free article.

4

Review article: inhibition of methanogenic archaea by statins as a targeted management strategy for constipation and related disorders.

Gottlieb K, Wacher V, Sliman J, Pimentel M. Gottlieb K, et al. Aliment Pharmacol Ther. 2016 Jan;43(2):197-212. doi: 10.1111/apt.13469. Epub 2015 Nov 11. Aliment Pharmacol Ther. 2016. PMID: 26559904 Free PMC article. Review.

5

Lovastatin lactone may improve irritable bowel syndrome with constipation (IBS-C) by inhibiting enzymes in the archaeal methanogenesis pathway.

Muskal SM, Sliman J, Kokai-Kun J, Pimentel M, Wacher V, Gottlieb K. Muskal SM, et al. F1000Res. 2016 Apr 8;5:606. doi: 10.12688/f1000research.8406.3. eCollection 2016. F1000Res. 2016. PMID: 27347377 Free PMC article.

6

Selection of a cut-off for high- and low-methane producers using a spot-methane breath test: results from a large north American dataset of hydrogen, methane and carbon dioxide measurements in breath.

Gottlieb K, Le C, Wacher V, Sliman J, Cruz C, Porter T, Carter S. Gottlieb K, et al. Gastroenterol Rep (Oxf). 2017 Aug;5(3):193-199. doi: 10.1093/gastro/gow048. Epub 2017 Jan 27. Gastroenterol Rep (Oxf). 2017. PMID: 28130375 Free PMC article.

7

Erratum: Selection of a cut-off for high- and low-methane producers using a spot-methane breath test: results from a large north American dataset of hydrogen, methane and carbon dioxide measurements in breath.

Gottlieb K, Le C, Wacher V, Sliman J, Cruz C, Porter T, Carter S. Gottlieb K, et al. Gastroenterol Rep (Oxf). 2018 Aug;6(3):242. doi: 10.1093/gastro/gox015. Epub 2017 Apr 27. Gastroenterol Rep (Oxf). 2018. PMID: 30151210 Free PMC article.

8

Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate.

Wacher VJ, Silverman JA, Wong S, Tran-Tau P, Chan AO, Chai A, Yu XQ, O'Mahony D, Ramtoola Z. Wacher VJ, et al. J Pharmacol Exp Ther. 2002 Oct;303(1):308-13. doi: 10.1124/jpet.102.036541. J Pharmacol Exp Ther. 2002. PMID: 12235265

9

Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin E TPGS.

Wempe MF, Wright C, Little JL, Lightner JW, Large SE, Caflisch GB, Buchanan CM, Rice PJ, Wacher VJ, Ruble KM, Edgar KJ. Wempe MF, et al. Among authors: wacher vj. Int J Pharm. 2009 Mar 31;370(1-2):93-102. doi: 10.1016/j.ijpharm.2008.11.021. Epub 2008 Nov 30. Int J Pharm. 2009. PMID: 19100824

10

Pharmacokinetics of saquinavir after intravenous and oral dosing of saquinavir: hydroxybutenyl-beta-cyclodextrin formulations.

Buchanan CM, Buchanan NL, Edgar KJ, Little JL, Ramsey MG, Ruble KM, Wacher VJ, Wempe MF. Buchanan CM, et al. Among authors: wacher vj. Biomacromolecules. 2008 Jan;9(1):305-13. doi: 10.1021/bm700827h. Epub 2007 Dec 12. Biomacromolecules. 2008. PMID: 18072746

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