Zhang DD - Search Results

1

Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action.

Kang MJ, Wu T, Wijeratne EM, Lau EC, Mason DJ, Mesa C, Tillotson J, Zhang DD, Gunatilaka AA, La Clair JJ, Chapman E. Kang MJ, et al. Among authors: zhang dd. Chembiochem. 2014 Sep 22;15(14):2125-31. doi: 10.1002/cbic.201402258. Epub 2014 Aug 14. Chembiochem. 2014. PMID: 25125376 Free PMC article.

2

Nrf2 promotes neuronal cell differentiation.

Zhao F, Wu T, Lau A, Jiang T, Huang Z, Wang XJ, Chen W, Wong PK, Zhang DD. Zhao F, et al. Among authors: zhang dd. Free Radic Biol Med. 2009 Sep 15;47(6):867-79. doi: 10.1016/j.freeradbiomed.2009.06.029. Epub 2009 Jun 30. Free Radic Biol Med. 2009. PMID: 19573594 Free PMC article.

3

A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.

Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. Lau A, et al. Among authors: zhang dd. Mol Cell Biol. 2010 Jul;30(13):3275-85. doi: 10.1128/MCB.00248-10. Epub 2010 Apr 26. Mol Cell Biol. 2010. PMID: 20421418 Free PMC article.

4

Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism.

Ren D, Villeneuve NF, Jiang T, Wu T, Lau A, Toppin HA, Zhang DD. Ren D, et al. Among authors: zhang dd. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1433-8. doi: 10.1073/pnas.1014275108. Epub 2011 Jan 4. Proc Natl Acad Sci U S A. 2011. PMID: 21205897 Free PMC article.

5

KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.

Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD. Sun Z, et al. Among authors: zhang dd. Mol Cell Biol. 2011 May;31(9):1800-11. doi: 10.1128/MCB.05036-11. Epub 2011 Mar 7. Mol Cell Biol. 2011. PMID: 21383067 Free PMC article.

6

USP15 negatively regulates Nrf2 through deubiquitination of Keap1.

Villeneuve NF, Tian W, Wu T, Sun Z, Lau A, Chapman E, Fang D, Zhang DD. Villeneuve NF, et al. Among authors: zhang dd. Mol Cell. 2013 Jul 11;51(1):68-79. doi: 10.1016/j.molcel.2013.04.022. Epub 2013 May 30. Mol Cell. 2013. PMID: 23727018 Free PMC article.

7

Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription.

Wu T, Wang XJ, Tian W, Jaramillo MC, Lau A, Zhang DD. Wu T, et al. Among authors: zhang dd. Free Radic Biol Med. 2014 Feb;67:69-80. doi: 10.1016/j.freeradbiomed.2013.10.806. Epub 2013 Oct 17. Free Radic Biol Med. 2014. PMID: 24140708 Free PMC article.

8

Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis.

Wu T, Zhao F, Gao B, Tan C, Yagishita N, Nakajima T, Wong PK, Chapman E, Fang D, Zhang DD. Wu T, et al. Among authors: zhang dd. Genes Dev. 2014 Apr 1;28(7):708-22. doi: 10.1101/gad.238246.114. Epub 2014 Mar 17. Genes Dev. 2014. PMID: 24636985 Free PMC article.

9

Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy?

Wu T, Harder BG, Wong PK, Lang JE, Zhang DD. Wu T, et al. Among authors: zhang dd. Mol Carcinog. 2015 Nov;54(11):1494-502. doi: 10.1002/mc.22202. Epub 2014 Aug 23. Mol Carcinog. 2015. PMID: 25154499 Free PMC article.

10

Oncogenic KRAS confers chemoresistance by upregulating NRF2.

Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD. Tao S, et al. Among authors: zhang dd. Cancer Res. 2014 Dec 15;74(24):7430-41. doi: 10.1158/0008-5472.CAN-14-1439. Epub 2014 Oct 22. Cancer Res. 2014. PMID: 25339352 Free PMC article.

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