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WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.
Chávez-Canales M, Zhang C, Soukaseum C, Moreno E, Pacheco-Alvarez D, Vidal-Petiot E, Castañeda-Bueno M, Vázquez N, Rojas-Vega L, Meermeier NP, Rogers S, Jeunemaitre X, Yang CL, Ellison DH, Gamba G, Hadchouel J. Chávez-Canales M, et al. Among authors: gamba g. Hypertension. 2014 Nov;64(5):1047-53. doi: 10.1161/HYPERTENSIONAHA.114.04036. Epub 2014 Aug 11. Hypertension. 2014. PMID: 25113964 Free PMC article.
Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes.
Mercado A, de los Heros P, Vázquez N, Meade P, Mount DB, Gamba G. Mercado A, et al. Among authors: gamba g. Am J Physiol Cell Physiol. 2001 Aug;281(2):C670-80. doi: 10.1152/ajpcell.2001.281.2.C670. Am J Physiol Cell Physiol. 2001. PMID: 11443066 Free article.
The predicted COOH-terminal protein fragment exhibited particular homology to the KCC1/KCC3 subgroup of the mammalian KCCs, and the functional characteristics are the most similar to those of KCC1 (Mercado A, Song L, Vazquez N, Mount DB, and Gamba G. J Biol Chem 275 …
The predicted COOH-terminal protein fragment exhibited particular homology to the KCC1/KCC3 subgroup of the mammalian KCCs, and the function …
Functional differences between flounder and rat thiazide-sensitive Na-Cl cotransporter.
Vázquez N, Monroy A, Dorantes E, Muñoz-Clares RA, Gamba G. Vázquez N, et al. Among authors: gamba g. Am J Physiol Renal Physiol. 2002 Apr;282(4):F599-607. doi: 10.1152/ajprenal.00284.2001. Am J Physiol Renal Physiol. 2002. PMID: 11880320 Free article.
The purpose of the present study was to determine the major functional, pharmacological, and regulatory properties of the flounder thiazide-sensitive Na-Cl cotransporter (flTSC) to make a direct comparison with our recent characterization of the rat TSC (rTSC; Monroy A, Plata C, …
The purpose of the present study was to determine the major functional, pharmacological, and regulatory properties of the flounder thiazide- …
A single nucleotide polymorphism alters the activity of the renal Na+:Cl- cotransporter and reveals a role for transmembrane segment 4 in chloride and thiazide affinity.
Moreno E, Tovar-Palacio C, de los Heros P, Guzmán B, Bobadilla NA, Vázquez N, Riccardi D, Poch E, Gamba G. Moreno E, et al. Among authors: gamba g. J Biol Chem. 2004 Apr 16;279(16):16553-60. doi: 10.1074/jbc.M400602200. Epub 2004 Feb 5. J Biol Chem. 2004. PMID: 14766743 Free article.
464 results