Garden GA - Search Results

1

Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA.

Cortes CJ, Miranda HC, Frankowski H, Batlevi Y, Young JE, Le A, Ivanov N, Sopher BL, Carromeu C, Muotri AR, Garden GA, La Spada AR. Cortes CJ, et al. Among authors: garden ga. Nat Neurosci. 2014 Sep;17(9):1180-9. doi: 10.1038/nn.3787. Epub 2014 Aug 10. Nat Neurosci. 2014. PMID: 25108912 Free PMC article.

2

Microglia specific deletion of miR-155 in Alzheimer's disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures.

Aloi MS, Prater KE, Sánchez REA, Beck A, Pathan JL, Davidson S, Wilson A, Keene CD, de la Iglesia H, Jayadev S, Garden GA. Aloi MS, et al. Among authors: garden ga. J Neuroinflammation. 2023 Mar 7;20(1):60. doi: 10.1186/s12974-023-02745-6. J Neuroinflammation. 2023. PMID: 36879321 Free PMC article.

3

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

Garden GA, Libby RT, Fu YH, Kinoshita Y, Huang J, Possin DE, Smith AC, Martinez RA, Fine GC, Grote SK, Ware CB, Einum DD, Morrison RS, Ptacek LJ, Sopher BL, La Spada AR. Garden GA, et al. J Neurosci. 2002 Jun 15;22(12):4897-905. doi: 10.1523/JNEUROSCI.22-12-04897.2002. J Neurosci. 2002. PMID: 12077187 Free PMC article.

4

Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport.

Custer SK, Garden GA, Gill N, Rueb U, Libby RT, Schultz C, Guyenet SJ, Deller T, Westrum LE, Sopher BL, La Spada AR. Custer SK, et al. Among authors: garden ga. Nat Neurosci. 2006 Oct;9(10):1302-11. doi: 10.1038/nn1750. Epub 2006 Aug 27. Nat Neurosci. 2006. PMID: 16936724

5

Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration.

Garden GA, La Spada AR. Garden GA, et al. Cerebellum. 2008;7(2):138-49. doi: 10.1007/s12311-008-0027-y. Cerebellum. 2008. PMID: 18418675 Free PMC article. Review.

6

Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.

Young JE, Garden GA, Martinez RA, Tanaka F, Sandoval CM, Smith AC, Sopher BL, Lin A, Fischbeck KH, Ellerby LM, Morrison RS, Taylor JP, La Spada AR. Young JE, et al. Among authors: garden ga. J Neurosci. 2009 Feb 18;29(7):1987-97. doi: 10.1523/JNEUROSCI.4072-08.2009. J Neurosci. 2009. PMID: 19228953 Free PMC article.

7

Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death.

Chakrabarti L, Eng J, Ivanov N, Garden GA, La Spada AR. Chakrabarti L, et al. Among authors: garden ga. Mol Brain. 2009 Jul 29;2:24. doi: 10.1186/1756-6606-2-24. Mol Brain. 2009. PMID: 19640278 Free PMC article.

8

A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia.

Guyenet SJ, Furrer SA, Damian VM, Baughan TD, La Spada AR, Garden GA. Guyenet SJ, et al. Among authors: garden ga. J Vis Exp. 2010 May 21;(39):1787. doi: 10.3791/1787. J Vis Exp. 2010. PMID: 20495529 Free PMC article.

9

Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration.

Furrer SA, Mohanachandran MS, Waldherr SM, Chang C, Damian VA, Sopher BL, Garden GA, La Spada AR. Furrer SA, et al. Among authors: garden ga. J Neurosci. 2011 Nov 9;31(45):16269-78. doi: 10.1523/JNEUROSCI.4000-11.2011. J Neurosci. 2011. PMID: 22072678 Free PMC article.

10

Intercellular (mis)communication in neurodegenerative disease.

Garden GA, La Spada AR. Garden GA, et al. Neuron. 2012 Mar 8;73(5):886-901. doi: 10.1016/j.neuron.2012.02.017. Neuron. 2012. PMID: 22405200 Free PMC article. Review.

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