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Page 1
Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model.
Bestas B, Moreno PM, Blomberg KE, Mohammad DK, Saleh AF, Sutlu T, Nordin JZ, Guterstam P, Gustafsson MO, Kharazi S, Piątosa B, Roberts TC, Behlke MA, Wood MJ, Gait MJ, Lundin KE, El Andaloussi S, Månsson R, Berglöf A, Wengel J, Smith CI. Bestas B, et al. Among authors: guterstam p. J Clin Invest. 2014 Sep;124(9):4067-81. doi: 10.1172/JCI76175. Epub 2014 Aug 8. J Clin Invest. 2014. PMID: 25105368 Free PMC article.
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation.
Ezzat K, Andaloussi SE, Zaghloul EM, Lehto T, Lindberg S, Moreno PM, Viola JR, Magdy T, Abdo R, Guterstam P, Sillard R, Hammond SM, Wood MJ, Arzumanov AA, Gait MJ, Smith CI, Hällbrink M, Langel Ü. Ezzat K, et al. Among authors: guterstam p. Nucleic Acids Res. 2011 Jul;39(12):5284-98. doi: 10.1093/nar/gkr072. Epub 2011 Feb 23. Nucleic Acids Res. 2011. PMID: 21345932 Free PMC article.
Distinct uptake routes of cell-penetrating peptide conjugates.
Lundin P, Johansson H, Guterstam P, Holm T, Hansen M, Langel U, EL Andaloussi S. Lundin P, et al. Among authors: guterstam p. Bioconjug Chem. 2008 Dec;19(12):2535-42. doi: 10.1021/bc800212j. Bioconjug Chem. 2008. PMID: 19012426
Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy.
Lehto T, Abes R, Oskolkov N, Suhorutsenko J, Copolovici DM, Mäger I, Viola JR, Simonson OE, Ezzat K, Guterstam P, Eriste E, Smith CI, Lebleu B, Samir El Andaloussi, Langel U. Lehto T, et al. Among authors: guterstam p. J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8. J Control Release. 2010. PMID: 19744531
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo.
Andaloussi SE, Lehto T, Mäger I, Rosenthal-Aizman K, Oprea II, Simonson OE, Sork H, Ezzat K, Copolovici DM, Kurrikoff K, Viola JR, Zaghloul EM, Sillard R, Johansson HJ, Said Hassane F, Guterstam P, Suhorutšenko J, Moreno PM, Oskolkov N, Hälldin J, Tedebark U, Metspalu A, Lebleu B, Lehtiö J, Smith CI, Langel U. Andaloussi SE, et al. Among authors: guterstam p. Nucleic Acids Res. 2011 May;39(9):3972-87. doi: 10.1093/nar/gkq1299. Epub 2011 Jan 17. Nucleic Acids Res. 2011. PMID: 21245043 Free PMC article.
15 results