Ouyang X - Search Results

1

Activation of N-methyl-d-aspartate receptor downregulates inflammasome activity and liver inflammation via a β-arrestin-2 pathway.

Farooq A, Hoque R, Ouyang X, Farooq A, Ghani A, Ahsan K, Guerra M, Mehal WZ. Farooq A, et al. Among authors: ouyang x. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1;307(7):G732-40. doi: 10.1152/ajpgi.00073.2014. Epub 2014 Aug 7. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 25104498 Free PMC article.

2

Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response.

Malik AF, Hoque R, Ouyang X, Ghani A, Hong E, Khan K, Moore LB, Ng G, Munro F, Flavell RA, Shi Y, Kyriakides TR, Mehal WZ. Malik AF, et al. Among authors: ouyang x. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20095-100. doi: 10.1073/pnas.1105152108. Epub 2011 Nov 22. Proc Natl Acad Sci U S A. 2011. PMID: 22109549 Free PMC article.

3

Inflammasome biology in fibrogenesis.

Ouyang X, Ghani A, Mehal WZ. Ouyang X, et al. Biochim Biophys Acta. 2013 Jul;1832(7):979-88. doi: 10.1016/j.bbadis.2013.03.020. Epub 2013 Apr 3. Biochim Biophys Acta. 2013. PMID: 23562491 Free article.

4

Adenosine is required for sustained inflammasome activation via the A₂A receptor and the HIF-1α pathway.

Ouyang X, Ghani A, Malik A, Wilder T, Colegio OR, Flavell RA, Cronstein BN, Mehal WZ. Ouyang X, et al. Nat Commun. 2013;4:2909. doi: 10.1038/ncomms3909. Nat Commun. 2013. PMID: 24352507 Free PMC article.

5

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9.

Garcia-Martinez I, Santoro N, Chen Y, Hoque R, Ouyang X, Caprio S, Shlomchik MJ, Coffman RL, Candia A, Mehal WZ. Garcia-Martinez I, et al. Among authors: ouyang x. J Clin Invest. 2016 Mar 1;126(3):859-64. doi: 10.1172/JCI83885. Epub 2016 Jan 25. J Clin Invest. 2016. PMID: 26808498 Free PMC article.

6

Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response.

Cai SY, Ouyang X, Chen Y, Soroka CJ, Wang J, Mennone A, Wang Y, Mehal WZ, Jain D, Boyer JL. Cai SY, et al. Among authors: ouyang x. JCI Insight. 2017 Mar 9;2(5):e90780. doi: 10.1172/jci.insight.90780. JCI Insight. 2017. PMID: 28289714 Free PMC article.

7

Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis.

Ouyang X, Han SN, Zhang JY, Dioletis E, Nemeth BT, Pacher P, Feng D, Bataller R, Cabezas J, Stärkel P, Caballeria J, Pongratz RL, Cai SY, Schnabl B, Hoque R, Chen Y, Yang WH, Garcia-Martinez I, Wang FS, Gao B, Torok NJ, Kibbey RG, Mehal WZ. Ouyang X, et al. Cell Metab. 2018 Feb 6;27(2):339-350.e3. doi: 10.1016/j.cmet.2018.01.007. Cell Metab. 2018. PMID: 29414684 Free PMC article.

8

β-Hydroxybutyrate protects from alcohol-induced liver injury via a Hcar2-cAMP dependent pathway.

Chen Y, Ouyang X, Hoque R, Garcia-Martinez I, Yousaf MN, Tonack S, Offermanns S, Dubuquoy L, Louvet A, Mathurin P, Massey V, Schnabl B, Bataller RA, Mehal WZ. Chen Y, et al. Among authors: ouyang x. J Hepatol. 2018 Sep;69(3):687-696. doi: 10.1016/j.jhep.2018.04.004. Epub 2018 Apr 27. J Hepatol. 2018. PMID: 29705237 Free PMC article.

9

The multi-dimensional role of intestinal HIFs in liver pathobiology.

Ouyang X, Mehal WZ. Ouyang X, et al. J Hepatol. 2018 Oct;69(4):772-773. doi: 10.1016/j.jhep.2018.07.012. Epub 2018 Aug 10. J Hepatol. 2018. PMID: 30104025 No abstract available.

10

Digoxin improves steatohepatitis with differential involvement of liver cell subsets in mice through inhibition of PKM2 transactivation.

Zhao P, Han SN, Arumugam S, Yousaf MN, Qin Y, Jiang JX, Torok NJ, Chen Y, Mankash MS, Liu J, Li J, Iwakiri Y, Ouyang X. Zhao P, et al. Among authors: ouyang x. Am J Physiol Gastrointest Liver Physiol. 2019 Oct 1;317(4):G387-G397. doi: 10.1152/ajpgi.00054.2019. Epub 2019 Aug 14. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 31411894 Free PMC article.

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