Bujons J - Search Results

1

Selective chaperone effect of aminocyclitol derivatives on G202R and other mutant glucocerebrosidases causing Gaucher disease.

Serra-Vinardell J, Díaz L, Gutiérrez-de Terán H, Sánchez-Ollé G, Bujons J, Michelakakis H, Mavridou I, Aerts JM, Delgado A, Grinberg D, Vilageliu L, Casas J. Serra-Vinardell J, et al. Among authors: bujons j. Int J Biochem Cell Biol. 2014 Sep;54:245-54. doi: 10.1016/j.biocel.2014.07.017. Epub 2014 Jul 30. Int J Biochem Cell Biol. 2014. PMID: 25084554

2

Click chemistry approach to new N-substituted aminocyclitols as potential pharmacological chaperones for Gaucher disease.

Díaz L, Bujons J, Casas J, Llebaria A, Delgado A. Díaz L, et al. Among authors: bujons j. J Med Chem. 2010 Jul 22;53(14):5248-55. doi: 10.1021/jm100198t. J Med Chem. 2010. PMID: 20557054

3

New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening.

Díaz L, Casas J, Bujons J, Llebaria A, Delgado A. Díaz L, et al. Among authors: bujons j. J Med Chem. 2011 Apr 14;54(7):2069-79. doi: 10.1021/jm101204u. Epub 2011 Mar 3. J Med Chem. 2011. PMID: 21370884

4

Computational prediction of structure-activity relationships for the binding of aminocyclitols to β-glucocerebrosidase.

Díaz L, Bujons J, Delgado A, Gutiérrez-de-Terán H, Åqvist J. Díaz L, et al. Among authors: bujons j. J Chem Inf Model. 2011 Mar 28;51(3):601-11. doi: 10.1021/ci100453a. Epub 2011 Mar 8. J Chem Inf Model. 2011. PMID: 21384831

5

Bacterial versus human sphingosine-1-phosphate lyase (S1PL) in the design of potential S1PL inhibitors.

Sanllehí P, Abad JL, Casas J, Bujons J, Delgado A. Sanllehí P, et al. Among authors: bujons j. Bioorg Med Chem. 2016 Sep 15;24(18):4381-4389. doi: 10.1016/j.bmc.2016.07.033. Epub 2016 Jul 18. Bioorg Med Chem. 2016. PMID: 27475537

6

Studies on the inhibition of sphingosine-1-phosphate lyase by stabilized reaction intermediates and stereodefined azido phosphates.

Sanllehí P, Abad JL, Bujons J, Casas J, Delgado A. Sanllehí P, et al. Among authors: bujons j. Eur J Med Chem. 2016 Nov 10;123:905-915. doi: 10.1016/j.ejmech.2016.08.008. Epub 2016 Aug 6. Eur J Med Chem. 2016. PMID: 27543882

7

The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells.

Sanllehí P, Casasampere M, Abad JL, Fabriàs G, López O, Bujons J, Casas J, Delgado A. Sanllehí P, et al. Among authors: bujons j. Chem Commun (Camb). 2017 May 11;53(39):5441-5444. doi: 10.1039/c7cc01659j. Chem Commun (Camb). 2017. PMID: 28462976

8

Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II.

Cingolani F, Casasampere M, Sanllehí P, Casas J, Bujons J, Fabrias G. Cingolani F, et al. Among authors: bujons j. J Lipid Res. 2014 Aug;55(8):1711-20. doi: 10.1194/jlr.M049759. Epub 2014 May 29. J Lipid Res. 2014. PMID: 24875537 Free PMC article.

9

Aldol additions of dihydroxyacetone phosphate to N-Cbz-amino aldehydes catalyzed by L-fuculose-1-phosphate aldolase in emulsion systems: inversion of stereoselectivity as a function of the acceptor aldehyde.

Espelt L, Bujons J, Parella T, Calveras J, Joglar J, Delgado A, Clapés P. Espelt L, et al. Among authors: bujons j. Chemistry. 2005 Feb 18;11(5):1392-401. doi: 10.1002/chem.200400648. Chemistry. 2005. PMID: 15669071

10

Dihydroxyacetone phosphate aldolase catalyzed synthesis of structurally diverse polyhydroxylated pyrrolidine derivatives and evaluation of their glycosidase inhibitory properties.

Calveras J, Egido-Gabás M, Gómez L, Casas J, Parella T, Joglar J, Bujons J, Clapés P. Calveras J, et al. Among authors: bujons j. Chemistry. 2009 Jul 27;15(30):7310-28. doi: 10.1002/chem.200900838. Chemistry. 2009. PMID: 19579240

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