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Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. Lee KS, et al. Among authors: ulu a. J Med Chem. 2014 Aug 28;57(16):7016-30. doi: 10.1021/jm500694p. Epub 2014 Aug 11. J Med Chem. 2014. PMID: 25079952 Free PMC article.
Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP.
Inceoglu B, Wagner K, Schebb NH, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose T, Brosnan R, Hammock BD. Inceoglu B, et al. Among authors: ulu a. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5093-7. doi: 10.1073/pnas.1101073108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383170 Free PMC article.
Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy.
Lee KSS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. Lee KSS, et al. Among authors: ulu a. J Med Chem. 2018 May 10;61(9):4271. doi: 10.1021/acs.jmedchem.8b00582. Epub 2018 Apr 27. J Med Chem. 2018. PMID: 29701466 Free PMC article. No abstract available.
Soluble epoxide hydrolase in atherosclerosis.
Wang YX, Ulu A, Zhang LN, Hammock B. Wang YX, et al. Among authors: ulu a. Curr Atheroscler Rep. 2010 May;12(3):174-83. doi: 10.1007/s11883-010-0108-5. Curr Atheroscler Rep. 2010. PMID: 20425256 Free PMC article. Review.
119 results