Rasche N - Search Results

1

A chemoenzymatic approach to protein immobilization onto crystalline cellulose nanoscaffolds.

Uth C, Zielonka S, Hörner S, Rasche N, Plog A, Orelma H, Avrutina O, Zhang K, Kolmar H. Uth C, et al. Among authors: rasche n. Angew Chem Int Ed Engl. 2014 Nov 10;53(46):12618-23. doi: 10.1002/anie.201404616. Epub 2014 Jul 28. Angew Chem Int Ed Engl. 2014. PMID: 25070515

2

Self-Assembled Hybrid Aptamer-Fc Conjugates for Targeted Delivery: A Modular Chemoenzymatic Approach.

Dickgiesser S, Rasche N, Nasu D, Middel S, Hörner S, Avrutina O, Diederichsen U, Kolmar H. Dickgiesser S, et al. Among authors: rasche n. ACS Chem Biol. 2015 Sep 18;10(9):2158-65. doi: 10.1021/acschembio.5b00315. Epub 2015 Jul 14. ACS Chem Biol. 2015. PMID: 26131766

3

PROLink-Single Step Circularization and Purification Procedure for the Generation of an Improved Variant of Human Growth Hormone.

Rasche N, Tonillo J, Rieker M, Becker S, Dorr B, Ter-Ovanesyan D, Betz UA, Hock B, Kolmar H. Rasche N, et al. Bioconjug Chem. 2016 May 18;27(5):1341-7. doi: 10.1021/acs.bioconjchem.6b00137. Epub 2016 May 5. Bioconjug Chem. 2016. PMID: 27108993

4

Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates.

Sellmann C, Doerner A, Knuehl C, Rasche N, Sood V, Krah S, Rhiel L, Messemer A, Wesolowski J, Schuette M, Becker S, Toleikis L, Kolmar H, Hock B. Sellmann C, et al. Among authors: rasche n. J Biol Chem. 2016 Nov 25;291(48):25106-25119. doi: 10.1074/jbc.M116.753491. Epub 2016 Sep 30. J Biol Chem. 2016. PMID: 27694443 Free PMC article.

5

Generation of human bispecific common light chain antibodies by combining animal immunization and yeast display.

Krah S, Schröter C, Eller C, Rhiel L, Rasche N, Beck J, Sellmann C, Günther R, Toleikis L, Hock B, Kolmar H, Becker S. Krah S, et al. Among authors: rasche n. Protein Eng Des Sel. 2017 Apr 1;30(4):291-301. doi: 10.1093/protein/gzw077. Protein Eng Des Sel. 2017. PMID: 28062646

6

Site-Specific Antibody-Drug Conjugation Using Microbial Transglutaminase.

Dickgiesser S, Deweid L, Kellner R, Kolmar H, Rasche N. Dickgiesser S, et al. Among authors: rasche n. Methods Mol Biol. 2019;2012:135-149. doi: 10.1007/978-1-4939-9546-2_8. Methods Mol Biol. 2019. PMID: 31161507

7

Site-Specific Conjugation of Thiol-Reactive Cytotoxic Agents to Nonnative Cysteines of Engineered Monoclonal Antibodies.

Dickgiesser S, Kellner R, Kolmar H, Rasche N. Dickgiesser S, et al. Among authors: rasche n. Methods Mol Biol. 2019;2033:1-14. doi: 10.1007/978-1-4939-9654-4_1. Methods Mol Biol. 2019. PMID: 31332743

8

Isolation of Anti-Hapten Antibodies by Fluorescence-Activated Cell Sorting of Yeast-Displayed B-Cell Receptor Gene Repertoires.

Jäger S, Krah S, Könning D, Rosskopf J, Dickgiesser S, Rasche N, Kolmar H, Hecht S, Schröter C. Jäger S, et al. Among authors: rasche n. Methods Mol Biol. 2020;2070:267-287. doi: 10.1007/978-1-4939-9853-1_15. Methods Mol Biol. 2020. PMID: 31625101

9

Generation and Biological Evaluation of Fc Antigen Binding Fragment-Drug Conjugates as a Novel Antibody-Based Format for Targeted Drug Delivery.

Jäger S, Wagner TR, Rasche N, Kolmar H, Hecht S, Schröter C. Jäger S, et al. Among authors: rasche n. Bioconjug Chem. 2021 Aug 18;32(8):1699-1710. doi: 10.1021/acs.bioconjchem.1c00240. Epub 2021 Jun 29. Bioconjug Chem. 2021. PMID: 34185508

10

Effect of Conjugation Site and Technique on the Stability and Pharmacokinetics of Antibody-Drug Conjugates.

Kaempffe A, Dickgiesser S, Rasche N, Paoletti A, Bertotti E, De Salve I, Sirtori FR, Kellner R, Könning D, Hecht S, Anderl J, Kolmar H, Schröter C. Kaempffe A, et al. Among authors: rasche n. J Pharm Sci. 2021 Dec;110(12):3776-3785. doi: 10.1016/j.xphs.2021.08.002. Epub 2021 Aug 4. J Pharm Sci. 2021. PMID: 34363839

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