Thompson LM - Search Results

1

A transgenic minipig model of Huntington's Disease.

Baxa M, Hruska-Plochan M, Juhas S, Vodicka P, Pavlok A, Juhasova J, Miyanohara A, Nejime T, Klima J, Macakova M, Marsala S, Weiss A, Kubickova S, Musilova P, Vrtel R, Sontag EM, Thompson LM, Schier J, Hansikova H, Howland DS, Cattaneo E, DiFiglia M, Marsala M, Motlik J. Baxa M, et al. Among authors: thompson lm. J Huntingtons Dis. 2013;2(1):47-68. doi: 10.3233/JHD-130001. J Huntingtons Dis. 2013. PMID: 25063429

2

Modeling protein homopolymeric repeats: possible polyglutamine structural motifs for Huntington's disease.

Lathrop RH, Casale M, Tobias DJ, Marsh JL, Thompson LM. Lathrop RH, et al. Among authors: thompson lm. Proc Int Conf Intell Syst Mol Biol. 1998;6:105-14. Proc Int Conf Intell Syst Mol Biol. 1998. PMID: 9783215

3

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.

Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, Wanker EE, Bates GP, Housman DE, Thompson LM. Steffan JS, et al. Among authors: thompson lm. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6763-8. doi: 10.1073/pnas.100110097. Proc Natl Acad Sci U S A. 2000. PMID: 10823891 Free PMC article.

4

Fly models of Huntington's disease.

Marsh JL, Pallos J, Thompson LM. Marsh JL, et al. Among authors: thompson lm. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R187-93. doi: 10.1093/hmg/ddg271. Epub 2003 Aug 12. Hum Mol Genet. 2003. PMID: 12925571 Free article. Review.

5

Autophagy regulates the processing of amino terminal huntingtin fragments.

Qin ZH, Wang Y, Kegel KB, Kazantsev A, Apostol BL, Thompson LM, Yoder J, Aronin N, DiFiglia M. Qin ZH, et al. Among authors: thompson lm. Hum Mol Genet. 2003 Dec 15;12(24):3231-44. doi: 10.1093/hmg/ddg346. Epub 2003 Oct 21. Hum Mol Genet. 2003. PMID: 14570716

6

SUMO modification of Huntingtin and Huntington's disease pathology.

Steffan JS, Agrawal N, Pallos J, Rockabrand E, Trotman LC, Slepko N, Illes K, Lukacsovich T, Zhu YZ, Cattaneo E, Pandolfi PP, Thompson LM, Marsh JL. Steffan JS, et al. Among authors: thompson lm. Science. 2004 Apr 2;304(5667):100-4. doi: 10.1126/science.1092194. Science. 2004. PMID: 15064418 Free article.

7

Mutant huntingtin alters MAPK signaling pathways in PC12 and striatal cells: ERK1/2 protects against mutant huntingtin-associated toxicity.

Apostol BL, Illes K, Pallos J, Bodai L, Wu J, Strand A, Schweitzer ES, Olson JM, Kazantsev A, Marsh JL, Thompson LM. Apostol BL, et al. Among authors: thompson lm. Hum Mol Genet. 2006 Jan 15;15(2):273-85. doi: 10.1093/hmg/ddi443. Epub 2005 Dec 5. Hum Mol Genet. 2006. PMID: 16330479 Free article.

8

Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: restoration by the neuroprotective compound CEP-1347.

Conforti P, Ramos C, Apostol BL, Simmons DA, Nguyen HP, Riess O, Thompson LM, Zuccato C, Cattaneo E. Conforti P, et al. Among authors: thompson lm. Mol Cell Neurosci. 2008 Sep;39(1):1-7. doi: 10.1016/j.mcn.2008.04.012. Epub 2008 May 10. Mol Cell Neurosci. 2008. PMID: 18571429

9

CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice.

Apostol BL, Simmons DA, Zuccato C, Illes K, Pallos J, Casale M, Conforti P, Ramos C, Roarke M, Kathuria S, Cattaneo E, Marsh JL, Thompson LM. Apostol BL, et al. Among authors: thompson lm. Mol Cell Neurosci. 2008 Sep;39(1):8-20. doi: 10.1016/j.mcn.2008.04.007. Epub 2008 Apr 24. Mol Cell Neurosci. 2008. PMID: 18602275 Free article.

10

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease.

Pallos J, Bodai L, Lukacsovich T, Purcell JM, Steffan JS, Thompson LM, Marsh JL. Pallos J, et al. Among authors: thompson lm. Hum Mol Genet. 2008 Dec 1;17(23):3767-75. doi: 10.1093/hmg/ddn273. Epub 2008 Sep 1. Hum Mol Genet. 2008. PMID: 18762557 Free PMC article.

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