Crook ZR - Search Results

1

Surveying the landscape of Huntington's disease mechanisms, measurements, and medicines.

Crook ZR, Housman DE. Crook ZR, et al. J Huntingtons Dis. 2013;2(4):405-36. doi: 10.3233/JHD-130072. J Huntingtons Dis. 2013. PMID: 25062729 Review.

2

Huntington's disease: can mice lead the way to treatment?

Crook ZR, Housman D. Crook ZR, et al. Neuron. 2011 Feb 10;69(3):423-35. doi: 10.1016/j.neuron.2010.12.035. Neuron. 2011. PMID: 21315254 Free PMC article. Review.

3

Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice.

Crook ZR, Housman DE. Crook ZR, et al. Proc Natl Acad Sci U S A. 2012 May 8;109(19):7487-92. doi: 10.1073/pnas.1204542109. Epub 2012 Apr 23. Proc Natl Acad Sci U S A. 2012. PMID: 22529362 Free PMC article.

4

In vivo identification of therapeutic constructs from pooled candidates in HD model mice.

Crook ZR, Housman DE. Crook ZR, et al. J Huntingtons Dis. 2013;2(4):437-41. doi: 10.3233/JHD-130073. J Huntingtons Dis. 2013. PMID: 25062730

5

Miniproteins as a Powerful Modality in Drug Development.

Crook ZR, Nairn NW, Olson JM. Crook ZR, et al. Trends Biochem Sci. 2020 Apr;45(4):332-346. doi: 10.1016/j.tibs.2019.12.008. Epub 2020 Jan 31. Trends Biochem Sci. 2020. PMID: 32014389 Free PMC article. Review.

6

Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets.

Crook ZR, Sevilla GP, Friend D, Brusniak MY, Bandaranayake AD, Clarke M, Gewe M, Mhyre AJ, Baker D, Strong RK, Bradley P, Olson JM. Crook ZR, et al. Nat Commun. 2017 Dec 21;8(1):2244. doi: 10.1038/s41467-017-02098-8. Nat Commun. 2017. PMID: 29269835 Free PMC article.

7

Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.

Crook ZR, Girard EJ, Sevilla GP, Brusniak MY, Rupert PB, Friend DJ, Gewe MM, Clarke M, Lin I, Ruff R, Pakiam F, Phi TD, Bandaranayake A, Correnti CE, Mhyre AJ, Nairn NW, Strong RK, Olson JM. Crook ZR, et al. Sci Transl Med. 2022 May 18;14(645):eabn0402. doi: 10.1126/scitranslmed.abn0402. Epub 2022 May 18. Sci Transl Med. 2022. PMID: 35584229 Free PMC article.

8

Mammalian Surface Display Screening of Diverse Cystine-Dense Peptide Libraries for Difficult-to-Drug Targets.

Crook ZR, Sevilla GP, Mhyre AJ, Olson JM. Crook ZR, et al. Methods Mol Biol. 2020;2070:363-396. doi: 10.1007/978-1-4939-9853-1_21. Methods Mol Biol. 2020. PMID: 31625107

9

Publisher Correction: Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets.

Crook ZR, Sevilla GP, Friend D, Brusniak MY, Bandaranayake AD, Clarke M, Gewe M, Mhyre AJ, Baker D, Strong RK, Bradley P, Olson JM. Crook ZR, et al. Nat Commun. 2018 Mar 9;9(1):1072. doi: 10.1038/s41467-018-03350-5. Nat Commun. 2018. PMID: 29523778 Free PMC article.

10

A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules.

Crook ZR, Girard E, Sevilla GP, Merrill M, Friend D, Rupert PB, Pakiam F, Nguyen E, Yin C, Ruff RO, Hopping G, Strand AD, Finton KAK, Coxon M, Mhyre AJ, Strong RK, Olson JM. Crook ZR, et al. J Mol Biol. 2020 Jun 26;432(14):3989-4009. doi: 10.1016/j.jmb.2020.04.002. Epub 2020 Apr 15. J Mol Biol. 2020. PMID: 32304700 Free PMC article.

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