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TIF1γ protein regulates epithelial-mesenchymal transition by operating as a small ubiquitin-like modifier (SUMO) E3 ligase for the transcriptional regulator SnoN1.
Ikeuchi Y, Dadakhujaev S, Chandhoke AS, Huynh MA, Oldenborg A, Ikeuchi M, Deng L, Bennett EJ, Harper JW, Bonni A, Bonni S. Ikeuchi Y, et al. Among authors: dadakhujaev s. J Biol Chem. 2014 Sep 5;289(36):25067-78. doi: 10.1074/jbc.M114.575878. Epub 2014 Jul 24. J Biol Chem. 2014. PMID: 25059663 Free PMC article.
A novel role for the SUMO E3 ligase PIAS1 in cancer metastasis.
Dadakhujaev S, Salazar-Arcila C, Netherton SJ, Chandhoke AS, Singla AK, Jirik FR, Bonni S. Dadakhujaev S, et al. Oncoscience. 2014 Mar 31;1(3):229-40. doi: 10.18632/oncoscience.27. eCollection 2014. Oncoscience. 2014. PMID: 25594015 Free PMC article.