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Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury.
Papa L, Akinyi L, Liu MC, Pineda JA, Tepas JJ 3rd, Oli MW, Zheng W, Robinson G, Robicsek SA, Gabrielli A, Heaton SC, Hannay HJ, Demery JA, Brophy GM, Layon J, Robertson CS, Hayes RL, Wang KK. Papa L, et al. Among authors: hayes rl. Crit Care Med. 2010 Jan;38(1):138-44. doi: 10.1097/CCM.0b013e3181b788ab. Crit Care Med. 2010. PMID: 19726976 Free PMC article.
Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention.
Papa L, Lewis LM, Falk JL, Zhang Z, Silvestri S, Giordano P, Brophy GM, Demery JA, Dixit NK, Ferguson I, Liu MC, Mo J, Akinyi L, Schmid K, Mondello S, Robertson CS, Tortella FC, Hayes RL, Wang KK. Papa L, et al. Among authors: hayes rl. Ann Emerg Med. 2012 Jun;59(6):471-83. doi: 10.1016/j.annemergmed.2011.08.021. Epub 2011 Nov 8. Ann Emerg Med. 2012. PMID: 22071014 Free PMC article.
Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial lesions and neurosurgical intervention.
Papa L, Lewis LM, Silvestri S, Falk JL, Giordano P, Brophy GM, Demery JA, Liu MC, Mo J, Akinyi L, Mondello S, Schmid K, Robertson CS, Tortella FC, Hayes RL, Wang KK. Papa L, et al. Among authors: hayes rl. J Trauma Acute Care Surg. 2012 May;72(5):1335-44. doi: 10.1097/TA.0b013e3182491e3d. J Trauma Acute Care Surg. 2012. PMID: 22673263 Free PMC article. Clinical Trial.
Predicting Clinical Outcomes 7-10 Years after Severe Traumatic Brain Injury: Exploring the Prognostic Utility of the IMPACT Lab Model and Cerebrospinal Fluid UCH-L1 and MAP-2.
Svingos AM, Robicsek SA, Hayes RL, Wang KK, Robertson CS, Brophy GM, Papa L, Gabrielli A, Hannay HJ, Bauer RM, Heaton SC. Svingos AM, et al. Among authors: hayes rl. Neurocrit Care. 2022 Aug;37(1):172-183. doi: 10.1007/s12028-022-01461-y. Epub 2022 Mar 1. Neurocrit Care. 2022. PMID: 35229233
alphaII-Spectrin breakdown product cerebrospinal fluid exposure metrics suggest differences in cellular injury mechanisms after severe traumatic brain injury.
Brophy GM, Pineda JA, Papa L, Lewis SB, Valadka AB, Hannay HJ, Heaton SC, Demery JA, Liu MC, Tepas JJ 3rd, Gabrielli A, Robicsek S, Wang KK, Robertson CS, Hayes RL. Brophy GM, et al. Among authors: hayes rl. J Neurotrauma. 2009 Apr;26(4):471-9. doi: 10.1089/neu.2008.0657. J Neurotrauma. 2009. PMID: 19206997 Free PMC article.
507 results