Chen LH - Search Results

1

Discovery of a Negative Allosteric Modulator of GABAB Receptors.

Chen LH, Sun B, Zhang Y, Xu TJ, Xia ZX, Liu JF, Nan FJ. Chen LH, et al. ACS Med Chem Lett. 2014 May 27;5(7):742-7. doi: 10.1021/ml500162z. eCollection 2014 Jul 10. ACS Med Chem Lett. 2014. PMID: 25050158 Free PMC article.

2

An activity-based probe reveals dynamic protein-protein interactions mediating IGF-1R transactivation by the GABA(B) receptor.

Lin X, Li X, Jiang M, Chen L, Xu C, Zhang W, Zhao H, Sun B, Xu X, Nan F, Liu J. Lin X, et al. Biochem J. 2012 May 1;443(3):627-34. doi: 10.1042/BJ20120188. Biochem J. 2012. PMID: 22394253

3

Single-cell chemical proteomics with an activity-based probe: identification of low-copy membrane proteins on primary neurons.

Xu F, Zhao H, Feng X, Chen L, Chen D, Zhang Y, Nan F, Liu J, Liu BF. Xu F, et al. Angew Chem Int Ed Engl. 2014 Jun 23;53(26):6730-3. doi: 10.1002/anie.201402363. Epub 2014 May 21. Angew Chem Int Ed Engl. 2014. PMID: 24850238

4

A negative allosteric modulator modulates GABAB-receptor signalling through GB2 subunits.

Sun B, Chen L, Liu L, Xia Z, Pin JP, Nan F, Liu J. Sun B, et al. Biochem J. 2016 Mar 15;473(6):779-87. doi: 10.1042/BJ20150979. Epub 2016 Jan 15. Biochem J. 2016. PMID: 26772870

5

Design and Synthesis of 2-Alkylpyrimidine-4,6-diol and 6-Alkylpyridine-2,4-diol as Potent GPR84 Agonists.

Liu Y, Zhang Q, Chen LH, Yang H, Lu W, Xie X, Nan FJ. Liu Y, et al. Among authors: chen lh. ACS Med Chem Lett. 2016 Mar 30;7(6):579-83. doi: 10.1021/acsmedchemlett.6b00025. eCollection 2016 Jun 9. ACS Med Chem Lett. 2016. PMID: 27326330 Free PMC article.

6

Effect of GR24 Stereoisomers on Plant Development in Arabidopsis.

Li S, Chen L, Li Y, Yao R, Wang F, Yang M, Gu M, Nan F, Xie D, Yan J. Li S, et al. Mol Plant. 2016 Oct 10;9(10):1432-1435. doi: 10.1016/j.molp.2016.06.012. Epub 2016 Jul 1. Mol Plant. 2016. PMID: 27378724 Free article. No abstract available.

7

Discovery of a novel calcium-sensitive fluorescent probe for α-ketoglutarate.

Gan LL, Chen LH, Nan FJ. Gan LL, et al. Among authors: chen lh. Acta Pharmacol Sin. 2017 Dec;38(12):1683-1690. doi: 10.1038/aps.2017.75. Epub 2017 Jul 17. Acta Pharmacol Sin. 2017. PMID: 28713156 Free PMC article.

8

Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists.

Chen LH, Zhang Q, Xie X, Nan FJ. Chen LH, et al. J Med Chem. 2020 Dec 24;63(24):15399-15409. doi: 10.1021/acs.jmedchem.0c01378. Epub 2020 Dec 2. J Med Chem. 2020. PMID: 33267584

9

Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development.

Li S, Li Y, Chen L, Zhang C, Wang F, Li H, Wang M, Wang Y, Nan F, Xie D, Yan J. Li S, et al. Plant J. 2021 Jul;107(1):67-76. doi: 10.1111/tpj.15274. Epub 2021 May 22. Plant J. 2021. PMID: 33860570 Free article.

10

GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages.

Zhang Q, Chen LH, Yang H, Fang YC, Wang SW, Wang M, Yuan QT, Wu W, Zhang YM, Liu ZJ, Nan FJ, Xie X. Zhang Q, et al. Among authors: chen lh. Acta Pharmacol Sin. 2022 Aug;43(8):2042-2054. doi: 10.1038/s41401-021-00825-y. Epub 2021 Dec 15. Acta Pharmacol Sin. 2022. PMID: 34912006 Free PMC article.

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