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Page 1
N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.
Ramachandran S, Hameed P S, Srivastava A, Shanbhag G, Morayya S, Rautela N, Awasthy D, Kavanagh S, Bharath S, Reddy J, Panduga V, Prabhakar KR, Saralaya R, Nanduri R, Raichurkar A, Menasinakai S, Achar V, Jiménez-Díaz MB, Martínez MS, Angulo-Barturen I, Ferrer S, Sanz LM, Gamo FJ, Duffy S, Avery VM, Waterson D, Lee MC, Coburn-Flynn O, Fidock DA, Iyer PS, Narayanan S, Hosagrahara V, Sambandamurthy VK. Ramachandran S, et al. Among authors: achar v. J Med Chem. 2014 Aug 14;57(15):6642-52. doi: 10.1021/jm500715u. Epub 2014 Jul 21. J Med Chem. 2014. PMID: 25007124
Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
Hameed P S, Patil V, Solapure S, Sharma U, Madhavapeddi P, Raichurkar A, Chinnapattu M, Manjrekar P, Shanbhag G, Puttur J, Shinde V, Menasinakai S, Rudrapatana S, Achar V, Awasthy D, Nandishaiah R, Humnabadkar V, Ghosh A, Narayan C, Ramya VK, Kaur P, Sharma S, Werngren J, Hoffner S, Panduga V, Kumar CN, Reddy J, Kumar K N M, Ganguly S, Bharath S, Bheemarao U, Mukherjee K, Arora U, Gaonkar S, Coulson M, Waterson D, Sambandamurthy VK, de Sousa SM. Hameed P S, et al. Among authors: achar v. J Med Chem. 2014 Jun 12;57(11):4889-905. doi: 10.1021/jm500432n. Epub 2014 May 23. J Med Chem. 2014. PMID: 24809953
4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.
Naik M, Humnabadkar V, Tantry SJ, Panda M, Narayan A, Guptha S, Panduga V, Manjrekar P, Jena LK, Koushik K, Shanbhag G, Jatheendranath S, Manjunatha MR, Gorai G, Bathula C, Rudrapatna S, Achar V, Sharma S, Ambady A, Hegde N, Mahadevaswamy J, Kaur P, Sambandamurthy VK, Awasthy D, Narayan C, Ravishankar S, Madhavapeddi P, Reddy J, Prabhakar K, Saralaya R, Chatterji M, Whiteaker J, McLaughlin B, Chiarelli LR, Riccardi G, Pasca MR, Binda C, Neres J, Dhar N, Signorino-Gelo F, McKinney JD, Ramachandran V, Shandil R, Tommasi R, Iyer PS, Narayanan S, Hosagrahara V, Kavanagh S, Dinesh N, Ghorpade SR. Naik M, et al. Among authors: achar v. J Med Chem. 2014 Jun 26;57(12):5419-34. doi: 10.1021/jm5005978. Epub 2014 Jun 11. J Med Chem. 2014. PMID: 24871036
A high-throughput cidality screen for Mycobacterium tuberculosis.
Kaur P, Ghosh A, Krishnamurthy RV, Bhattacharjee DG, Achar V, Datta S, Narayanan S, Anbarasu A, Ramaiah S. Kaur P, et al. Among authors: achar v. PLoS One. 2015 Feb 18;10(2):e0117577. doi: 10.1371/journal.pone.0117577. eCollection 2015. PLoS One. 2015. PMID: 25693161 Free PMC article.
Simple and rapid method to determine antimycobacterial potency of compounds by using autoluminescent Mycobacterium tuberculosis.
Sharma S, Gelman E, Narayan C, Bhattacharjee D, Achar V, Humnabadkar V, Balasubramanian V, Ramachandran V, Dhar N, Dinesh N. Sharma S, et al. Among authors: achar v. Antimicrob Agents Chemother. 2014 Oct;58(10):5801-8. doi: 10.1128/AAC.03205-14. Epub 2014 Jul 21. Antimicrob Agents Chemother. 2014. PMID: 25049243 Free PMC article.
Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system.
Bellale E, Naik M, V B V, Ambady A, Narayan A, Ravishankar S, Ramachandran V, Kaur P, McLaughlin R, Whiteaker J, Morayya S, Guptha S, Sharma S, Raichurkar A, Awasthy D, Achar V, Vachaspati P, Bandodkar B, Panda M, Chatterji M. Bellale E, et al. Among authors: achar v. J Med Chem. 2014 Aug 14;57(15):6572-82. doi: 10.1021/jm500833f. Epub 2014 Jul 16. J Med Chem. 2014. PMID: 24967731
Biochemical comparison of migraine and stroke.
Welch KM, Chabi E, Nell JH, Nartosh K, Chee AN, Mathew NT, Achar VS. Welch KM, et al. Among authors: achar vs. Headache. 1976 Sep;16(4):160-7. doi: 10.1111/j.1526-4610.1976.hed1604160.x. Headache. 1976. PMID: 184066 No abstract available.
13 results