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Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, Robbins DJ. Li B, et al. Cancer Res. 2014 Sep 1;74(17):4811-21. doi: 10.1158/0008-5472.CAN-14-0317. Epub 2014 Jul 3. Cancer Res. 2014. PMID: 24994715 Free PMC article.
Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.
Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ. Li B, et al. Sci Signal. 2017 Jun 27;10(485):eaak9916. doi: 10.1126/scisignal.aak9916. Sci Signal. 2017. PMID: 28655862 Free PMC article.
APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway.
Saito-Diaz K, Benchabane H, Tiwari A, Tian A, Li B, Thompson JJ, Hyde AS, Sawyer LM, Jodoin JN, Santos E, Lee LA, Coffey RJ, Beauchamp RD, Williams CS, Kenworthy AK, Robbins DJ, Ahmed Y, Lee E. Saito-Diaz K, et al. Among authors: li b. Dev Cell. 2018 Mar 12;44(5):566-581.e8. doi: 10.1016/j.devcel.2018.02.013. Dev Cell. 2018. PMID: 29533772 Free PMC article.
Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma.
Wang Z, Da Silva TG, Jin K, Han X, Ranganathan P, Zhu X, Sanchez-Mejias A, Bai F, Li B, Fei DL, Weaver K, Carpio RV, Moscowitz AE, Koshenkov VP, Sanchez L, Sparling L, Pei XH, Franceschi D, Ribeiro A, Robbins DJ, Livingstone AS, Capobianco AJ. Wang Z, et al. Among authors: li b. Cancer Res. 2014 Nov 1;74(21):6364-74. doi: 10.1158/0008-5472.CAN-14-2051. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164006 Free PMC article.
Casein kinase1α activators, a precision weapon for CRC.
Li B, Lee E, Robbins DJ. Li B, et al. Oncotarget. 2017 Oct 19;8(57):96462-96463. doi: 10.18632/oncotarget.21892. eCollection 2017 Nov 14. Oncotarget. 2017. PMID: 29228537 Free PMC article. No abstract available.
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