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The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.
Batalha VL, Ferreira DG, Coelho JE, Valadas JS, Gomes R, Temido-Ferreira M, Shmidt T, Baqi Y, Buée L, Müller CE, Hamdane M, Outeiro TF, Bader M, Meijsing SH, Sadri-Vakili G, Blum D, Lopes LV. Batalha VL, et al. Among authors: valadas js. Sci Rep. 2016 Aug 11;6:31493. doi: 10.1038/srep31493. Sci Rep. 2016. PMID: 27510168 Free PMC article.
p13 protects against Parkinson's disease.
Valadas JS, Verstreken P. Valadas JS, et al. EMBO Rep. 2018 Mar;19(3):e45900. doi: 10.15252/embr.201845900. Epub 2018 Feb 19. EMBO Rep. 2018. PMID: 29459485 Free PMC article.
HDAC6 is a Bruchpilot deacetylase that facilitates neurotransmitter release.
Miskiewicz K, Jose LE, Yeshaw WM, Valadas JS, Swerts J, Munck S, Feiguin F, Dermaut B, Verstreken P. Miskiewicz K, et al. Among authors: valadas js. Cell Rep. 2014 Jul 10;8(1):94-102. doi: 10.1016/j.celrep.2014.05.051. Epub 2014 Jun 26. Cell Rep. 2014. PMID: 24981865 Free article.
12 results