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Using pharmacokinetic and viral kinetic modeling to estimate the antiviral effectiveness of telaprevir, boceprevir, and pegylated interferon during triple therapy in treatment-experienced hepatitis C virus-infected cirrhotic patients.
Antimicrob Agents Chemother. 2014 Sep;58(9):5332-41. doi: 10.1128/AAC.02611-14. Epub 2014 Jun 30.
Antimicrob Agents Chemother. 2014.
PMID: 24982076
Free PMC article.
Clinical Trial.
A Model-Based Illustrative Exploratory Approach to Optimize the Dosing of Peg-IFN/RBV in Cirrhotic Hepatitis C Patients Treated With Triple Therapy.
Laouénan C, Guedj J, Peytavin G, Nguyen TT, Lapalus M, Khelifa-Mouri F, Boyer N, Zoulim F, Serfaty L, Bronowicki JP, Martinot-Peignoux M, Lada O, Asselah T, Dorival C, Hézode C, Carrat F, Nicot F, Marcellin P, Mentré F.
Laouénan C, et al. Among authors: khelifa mouri f.
CPT Pharmacometrics Syst Pharmacol. 2015 Jan;4(1):e00008. doi: 10.1002/psp4.8. Epub 2014 Dec 30.
CPT Pharmacometrics Syst Pharmacol. 2015.
PMID: 26225222
Free PMC article.
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