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GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease.
Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee DY, Hong J, Kim HY, Oh SJ, Park SJ, Lee H, Yoon BE, Kim Y, Jeong Y, Shim I, Bae YC, Cho J, Kowall NW, Ryu H, Hwang E, Kim D, Lee CJ. Jo S, et al. Among authors: chun h, chun ye. Nat Med. 2014 Aug;20(8):886-96. doi: 10.1038/nm.3639. Epub 2014 Jun 29. Nat Med. 2014. PMID: 24973918 Free PMC article.
Glial GABA, synthesized by monoamine oxidase B, mediates tonic inhibition.
Yoon BE, Woo J, Chun YE, Chun H, Jo S, Bae JY, An H, Min JO, Oh SJ, Han KS, Kim HY, Kim T, Kim YS, Bae YC, Lee CJ. Yoon BE, et al. Among authors: chun h, chun ye. J Physiol. 2014 Nov 15;592(22):4951-68. doi: 10.1113/jphysiol.2014.278754. Epub 2014 Sep 19. J Physiol. 2014. PMID: 25239459 Free PMC article.
Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease.
Park JH, Ju YH, Choi JW, Song HJ, Jang BK, Woo J, Chun H, Kim HJ, Shin SJ, Yarishkin O, Jo S, Park M, Yeon SK, Kim S, Kim J, Nam MH, Londhe AM, Kim J, Cho SJ, Cho S, Lee C, Hwang SY, Kim SW, Oh SJ, Cho J, Pae AN, Lee CJ, Park KD. Park JH, et al. Among authors: chun h. Sci Adv. 2019 Mar 20;5(3):eaav0316. doi: 10.1126/sciadv.aav0316. eCollection 2019 Mar. Sci Adv. 2019. PMID: 30906861 Free PMC article.
2,012 results