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CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.
Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, Nieto-Arellano R, Tena JJ, Rollan I, Alvarez A, Torroja C, Caceres EF, Roy AR, Galjart N, Delgado-Olguin P, Sanchez-Cabo F, Enriquez JA, Gomez-Skarmeta JL, Manzanares M. Gomez-Velazquez M, et al. Among authors: manzanares m. PLoS Genet. 2017 Aug 28;13(8):e1006985. doi: 10.1371/journal.pgen.1006985. eCollection 2017 Aug. PLoS Genet. 2017. PMID: 28846746 Free PMC article.
The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.
Sainz de Aja J, Menchero S, Rollan I, Barral A, Tiana M, Jawaid W, Cossio I, Alvarez A, Carreño-Tarragona G, Badia-Careaga C, Nichols J, Göttgens B, Isern J, Manzanares M. Sainz de Aja J, et al. Among authors: manzanares m. EMBO J. 2019 Apr 1;38(7):e99122. doi: 10.15252/embj.201899122. Epub 2019 Feb 27. EMBO J. 2019. PMID: 30814124 Free PMC article.
Nanog regulates Pou3f1 expression at the exit from pluripotency during gastrulation.
Barral A, Rollan I, Sanchez-Iranzo H, Jawaid W, Badia-Careaga C, Menchero S, Gomez MJ, Torroja C, Sanchez-Cabo F, Göttgens B, Manzanares M, Sainz de Aja J. Barral A, et al. Among authors: manzanares m. Biol Open. 2019 Dec 2;8(11):bio046367. doi: 10.1242/bio.046367. Biol Open. 2019. PMID: 31791948 Free PMC article.
An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms.
Tapial J, Ha KCH, Sterne-Weiler T, Gohr A, Braunschweig U, Hermoso-Pulido A, Quesnel-Vallières M, Permanyer J, Sodaei R, Marquez Y, Cozzuto L, Wang X, Gómez-Velázquez M, Rayon T, Manzanares M, Ponomarenko J, Blencowe BJ, Irimia M. Tapial J, et al. Among authors: manzanares m. Genome Res. 2017 Oct;27(10):1759-1768. doi: 10.1101/gr.220962.117. Epub 2017 Aug 30. Genome Res. 2017. PMID: 28855263 Free PMC article.
Pluripotency factors regulate the onset of Hox cluster activation in the early embryo.
Tiana M, Lopez-Jimenez E, de Aja JS, Barral A, Victorino J, Badia-Careaga C, Rollan I, Rouco R, Santos E, Sanchez-Iranzo H, Acemel RD, Torroja C, Adan J, Andres-Leon E, Gomez-Skarmeta JL, Giovinazzo G, Sanchez-Cabo F, Manzanares M. Tiana M, et al. Among authors: manzanares m. Sci Adv. 2022 Jul 15;8(28):eabo3583. doi: 10.1126/sciadv.abo3583. Epub 2022 Jul 15. Sci Adv. 2022. PMID: 35857513 Free PMC article.
154 results