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Serum glucocorticoid inducible kinase (SGK)-1 protects endothelial cells against oxidative stress and apoptosis induced by hyperglycaemia.
Ferrelli F, Pastore D, Capuani B, Lombardo MF, Blot-Chabaud M, Coppola A, Basello K, Galli A, Donadel G, Romano M, Caratelli S, Pacifici F, Arriga R, Di Daniele N, Sbraccia P, Sconocchia G, Bellia A, Tesauro M, Federici M, Della-Morte D, Lauro D. Ferrelli F, et al. Acta Diabetol. 2015 Feb;52(1):55-64. doi: 10.1007/s00592-014-0600-4. Epub 2014 Jun 25. Acta Diabetol. 2015. PMID: 24961472
Therapeutic targeting of soluble CD146/MCAM with the M2J-1 monoclonal antibody prevents metastasis development and procoagulant activity in CD146-positive invasive tumors.
Stalin J, Traboulsi W, Vivancos-Stalin L, Nollet M, Joshkon A, Bachelier R, Guillet B, Lacroix R, Foucault-Bertaud A, Leroyer AS, Dignat-George F, Bardin N, Blot-Chabaud M. Stalin J, et al. Int J Cancer. 2020 Sep 15;147(6):1666-1679. doi: 10.1002/ijc.32909. Epub 2020 Feb 22. Int J Cancer. 2020. PMID: 32022257
CD146 mediates VEGF-induced melanoma cell extravasation through FAK activation.
Jouve N, Bachelier R, Despoix N, Blin MG, Matinzadeh MK, Poitevin S, Aurrand-Lions M, Fallague K, Bardin N, Blot-Chabaud M, Vely F, Dignat-George F, Leroyer AS. Jouve N, et al. Int J Cancer. 2015 Jul 1;137(1):50-60. doi: 10.1002/ijc.29370. Epub 2014 Dec 11. Int J Cancer. 2015. PMID: 25449773
Soluble CD146 is a predictive marker of pejorative evolution and of sunitinib efficacy in clear cell renal cell carcinoma.
Dufies M, Nollet M, Ambrosetti D, Traboulsi W, Viotti J, Borchiellini D, Grépin R, Parola J, Giuliano S, Helley-Russick D, Bensalah K, Ravaud A, Bernhard JC, Schiappa R, Bardin N, Dignat-George F, Rioux-Leclercq N, Oudard S, Négrier S, Ferrero JM, Chamorey E, Blot-Chabaud M, Pagès G. Dufies M, et al. Theranostics. 2018 Mar 28;8(9):2447-2458. doi: 10.7150/thno.23002. eCollection 2018. Theranostics. 2018. PMID: 29721091 Free PMC article. Clinical Trial.
Involvement of Multiple Variants of Soluble CD146 in Systemic Sclerosis: Identification of a Novel Profibrotic Factor.
Nollet M, Bachelier R, Joshkon A, Traboulsi W, Mahieux A, Moyon A, Muller A, Somasundaram I, Simoncini S, Peiretti F, Leroyer AS, Guillet B, Granel B, Dignat-George F, Bardin N, Foucault-Bertaud A, Blot-Chabaud M. Nollet M, et al. Arthritis Rheumatol. 2022 Jun;74(6):1027-1038. doi: 10.1002/art.42063. Epub 2022 Apr 11. Arthritis Rheumatol. 2022. PMID: 35001552
88 results