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The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity.
Tourette C, Farina F, Vazquez-Manrique RP, Orfila AM, Voisin J, Hernandez S, Offner N, Parker JA, Menet S, Kim J, Lyu J, Choi SH, Cormier K, Edgerly CK, Bordiuk OL, Smith K, Louise A, Halford M, Stacker S, Vert JP, Ferrante RJ, Lu W, Neri C. Tourette C, et al. Among authors: kim j. PLoS Biol. 2014 Jun 24;12(6):e1001895. doi: 10.1371/journal.pbio.1001895. eCollection 2014 Jun. PLoS Biol. 2014. PMID: 24960609 Free PMC article.
Inhibition of mitochondrial protein import by mutant huntingtin.
Yano H, Baranov SV, Baranova OV, Kim J, Pan Y, Yablonska S, Carlisle DL, Ferrante RJ, Kim AH, Friedlander RM. Yano H, et al. Among authors: kim ah, kim j. Nat Neurosci. 2014 Jun;17(6):822-31. doi: 10.1038/nn.3721. Epub 2014 May 18. Nat Neurosci. 2014. PMID: 24836077 Free PMC article.
Reduced creatine kinase as a central and peripheral biomarker in Huntington's disease.
Kim J, Amante DJ, Moody JP, Edgerly CK, Bordiuk OL, Smith K, Matson SA, Matson WR, Scherzer CR, Rosas HD, Hersch SM, Ferrante RJ. Kim J, et al. Biochim Biophys Acta. 2010 Jul-Aug;1802(7-8):673-81. doi: 10.1016/j.bbadis.2010.05.001. Epub 2010 May 9. Biochim Biophys Acta. 2010. PMID: 20460152 Free PMC article.
Uridine ameliorates the pathological phenotype in transgenic G93A-ALS mice.
Amante DJ, Kim J, Carreiro ST, Cooper AC, Jones SW, Li T, Moody JP, Edgerly CK, Bordiuk OL, Cormier K, Smith K, Ferrante RJ, Rusche J. Amante DJ, et al. Among authors: kim j. Amyotroph Lateral Scler. 2010 Dec;11(6):520-30. doi: 10.3109/17482968.2010.491867. Epub 2010 Jun 22. Amyotroph Lateral Scler. 2010. PMID: 20565334
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